Uridylate-specific_endoribonuclease Google Drive Data
Uridylate-specific endoribonuclease (NendoU) (nsp 15)– NendoU cleaves 2′-3′-cyclic phosphates 5′, and it is Mn2+-dependent.2 The functionally active form of the endoribonuclease is a hexamer. The SARS-CoV-2 NendoU protein structure is homologous to SARS-CoV and MERS-CoV. SARS-CoV NendoU inhibitors have good chance of inhibiting the SARS-CoV-2 homolog but inhibitors of MERS-CoV NendoU are unlikely to be effective.25 Based on an in silico study, 2-deoxy-D-glucose can inactivate 3CLpro and nsp15 endoribonuclease.11 One study suggests that the inhaled corticosteroid ciclesonide targets NendoU and blocks coronavirus RNA replication.26

Uridylate-specific endoribonuclease 2,489 Sequences
Amino Acid | AA | AA | Conservation | Conservation Z-score | RMSD_CA | RMSF[A] | Secondary Structure | DCCM >0.9 |
6453 | S | SER | 48.97549217 | 0.058285975 | 1.552 | 1.592 | H | 0 |
6454 | L | LEU | 82.64363198 | 1.015679007 | 1.29 | 1.689 | H | 0 |
6455 | E | GLU | 82.44274809 | 1.009966638 | 1.324 | 1.355 | H | 2 |
6456 | N | ASN | 98.553636 | 1.468098625 | 1.287 | 1.136 | H | 4 |
6457 | V | VAL | 28.96745681 | -0.51066597 | 1.032 | 1.042 | H | 1 |
6458 | A | ALA | 82.9650462 | 1.024818797 | 1.134 | 1.068 | H | 1 |
6459 | F | PHE | 52.59140217 | 0.161108615 | 1.293 | 1.295 | H | 2 |
6460 | N | ASN | 99.23664122 | 1.48752068 | 1.191 | 1.023 | H | 1 |
6461 | V | VAL | 61.55082362 | 0.415880269 | 1.283 | 1.08 | H | 1 |
6462 | V | VAL | 73.16191241 | 0.746055193 | 1.639 | 1.488 | H | 2 |
6463 | N | ASN | 12.97709924 | -0.965370537 | 1.861 | 1.757 | H | 2 |
6464 | K | LYS | 48.85496183 | 0.054858553 | 2.529 | 1.911 | H | 1 |
6465 | G | GLY | 94.29489755 | 1.346996404 | 2.508 | 1.161 | C | 0 |
6466 | H | HIS | 57.05102451 | 0.287923205 | 1.376 | 1.153 | C | 0 |
6467 | F | PHE | 64.28284452 | 0.493568487 | 1.102 | 0.978 | C | 0 |
6468 | D | ASP | 28.68621937 | -0.518663287 | 1.49 | 1.385 | C | 0 |
6469 | G | GLY | 73.3627963 | 0.751767562 | 1.277 | 1.328 | C | 0 |
6470 | Q | GLN | 15.66894335 | -0.888824793 | 1.799 | 1.741 | C | 1 |
6471 | Q | GLN | 2.531137003 | -1.262413721 | 1.809 | 2.303 | C | 2 |
6472 | G | GLY | 98.99558055 | 1.480665837 | 1.786 | 1.479 | C | 3 |
6473 | E | GLU | 89.11209321 | 1.199617286 | 1.645 | 1.604 | C | 4 |
6474 | V | VAL | 3.013258337 | -1.248704035 | 1.737 | 1.504 | C | 2 |
6475 | P | PRO | 94.61631177 | 1.356136194 | 1.844 | 1.717 | E | 1 |
6476 | V | VAL | 62.35435918 | 0.438729745 | 1.485 | 1.777 | E | 0 |
6477 | S | SER | 8.276416231 | -1.099039969 | 1.723 | 1.544 | E | 0 |
6478 | I | ILE | 46.24347127 | -0.019402243 | 1.572 | 1.446 | E | 1 |
6479 | I | ILE | 24.18642025 | -0.646620351 | 1.855 | 1.787 | E | 2 |
6480 | N | ASN | 71.71554841 | 0.704926137 | 2.451 | 1.905 | T | 2 |
6481 | N | ASN | 12.93692246 | -0.96651301 | 1.673 | 1.536 | T | 1 |
6482 | T | THR | 2.531137003 | -1.262413721 | 1.785 | 1.336 | E | 1 |
6483 | V | VAL | 77.50100442 | 0.869442362 | 1.636 | 1.152 | E | 2 |
6484 | Y | TYR | 13.74045802 | -0.943663535 | 1.755 | 1.443 | E | 2 |
6485 | T | THR | 30.89594215 | -0.455827229 | 1.792 | 1.459 | E | 2 |
6486 | K | LYS | 45.56046605 | -0.038824297 | 1.874 | 2.388 | E | 1 |
6487 | V | VAL | 12.81639213 | -0.969940432 | 2.099 | 2.528 | E | 1 |
6488 | D | ASP | 24.70871836 | -0.631768191 | 3.193 | 3.013 | T | 1 |
6489 | G | GLY | 25.9140217 | -0.597493978 | 2.874 | 2.6 | T | 0 |
6490 | V | VAL | 40.13660104 | -0.193058258 | 2.325 | 2.735 | E | 1 |
6491 | D | ASP | 78.10365609 | 0.886579469 | 2.111 | 2.069 | E | 1 |
6492 | V | VAL | 27.76215348 | -0.544940184 | 1.639 | 2.054 | E | 1 |
6493 | E | GLU | 8.356769787 | -1.096755022 | 1.509 | 1.859 | E | 2 |
6494 | L | LEU | 8.356769787 | -1.096755022 | 1.618 | 1.485 | E | 2 |
6495 | F | PHE | 99.11611089 | 1.484093258 | 1.534 | 0.978 | E | 1 |
6496 | E | GLU | 25.47207714 | -0.610061189 | 1.593 | 1.434 | C | 1 |
6497 | N | ASN | 99.23664122 | 1.48752068 | 1.518 | 1.077 | C | 1 |
6498 | K | LYS | 60.26516673 | 0.379321108 | 2.207 | 1.984 | C | 0 |
6499 | T | THR | 98.915227 | 1.478380889 | 1.887 | 1.562 | C | 0 |
6500 | T | THR | 54.47971073 | 0.214804883 | 1.966 | 1.729 | C | 0 |
6501 | L | LEU | 84.17034954 | 1.05909301 | 1.465 | 1.378 | C | 0 |
6502 | P | PRO | 99.07593411 | 1.482950785 | 1.229 | 1.178 | H | 0 |
6503 | V | VAL | 12.97709924 | -0.965370537 | 1.128 | 1.45 | H | 0 |
6504 | N | ASN | 77.86259542 | 0.879724626 | 1.331 | 1.376 | H | 0 |
6505 | V | VAL | 76.89835275 | 0.852305255 | 0.965 | 1.053 | H | 0 |
6506 | A | ALA | 99.276818 | 1.488663153 | 1.023 | 0.879 | H | 0 |
6507 | F | PHE | 84.4114102 | 1.065947853 | 1.016 | 0.764 | H | 0 |
6508 | E | GLU | 99.31699478 | 1.489805627 | 0.875 | 0.737 | H | 0 |
6509 | L | LEU | 94.41542788 | 1.350423825 | 0.99 | 1.097 | H | 0 |
6510 | W | TRP | 9.160305344 | -1.073905546 | 1.013 | 0.813 | H | 0 |
6511 | A | ALA | 92.64764966 | 1.300154979 | 1.021 | 0.804 | H | 0 |
6512 | K | LYS | 93.93330655 | 1.33671414 | 0.911 | 0.779 | E | 0 |
6513 | R | ARG | 99.11611089 | 1.484093258 | 1.263 | 1.132 | E | 0 |
6514 | N | ASN | 25.5524307 | -0.607776242 | 1.309 | 1.395 | E | 0 |
6515 | I | ILE | 34.83326637 | -0.343864798 | 1.422 | 1.335 | C | 0 |
6516 | K | LYS | 9.200482121 | -1.072763072 | 0.927 | 1.569 | C | 0 |
6517 | P | PRO | 9.6022499 | -1.061338335 | 1.429 | 1.033 | C | 0 |
6518 | V | VAL | 9.079951788 | -1.076190494 | 1.787 | 1.075 | E | 0 |
6519 | P | PRO | 99.31699478 | 1.489805627 | 1.202 | 0.793 | C | 0 |
6520 | E | GLU | 24.10606669 | -0.648905298 | 1.085 | 0.709 | H | 0 |
6521 | V | VAL | 3.173965448 | -1.24413414 | 1.517 | 0.878 | H | 0 |
6522 | K | LYS | 40.2169546 | -0.19077331 | 1.538 | 0.934 | H | 0 |
6523 | I | ILE | 61.91241462 | 0.426162533 | 1.213 | 0.97 | H | 0 |
6524 | L | LEU | 86.58095621 | 1.127641437 | 1.607 | 0.869 | H | 0 |
6525 | N | ASN | 8.316593009 | -1.097897496 | 1.826 | 0.747 | H | 0 |
6526 | N | ASN | 77.70188831 | 0.875154731 | 1.483 | 0.647 | H | 0 |
6527 | L | LEU | 98.15186822 | 1.456673887 | 1.526 | 0.865 | H | 0 |
6528 | G | GLY | 66.81398152 | 0.565544335 | 1.837 | 0.689 | C | 0 |
6529 | V | VAL | 69.58617919 | 0.644375026 | 1.498 | 0.839 | C | 0 |
6530 | D | ASP | 56.85014062 | 0.282210837 | 1.546 | 0.762 | C | 0 |
6531 | I | ILE | 26.03455203 | -0.594066556 | 1.493 | 0.863 | E | 0 |
6532 | A | ALA | 8.798714343 | -1.08418781 | 1.639 | 0.83 | E | 0 |
6533 | A | ALA | 8.597830454 | -1.089900179 | 1.93 | 1.15 | E | 0 |
6534 | N | ASN | 15.14664524 | -0.903676952 | 1.803 | 1.292 | C | 0 |
6535 | T | THR | 7.995178787 | -1.107037286 | 1.13 | 0.978 | C | 0 |
6536 | V | VAL | 93.12977099 | 1.313864664 | 1.621 | 1.229 | E | 0 |
6537 | I | ILE | 58.61791884 | 0.332479683 | 2.17 | 1.32 | E | 0 |
6538 | W | TRP | 99.35717155 | 1.490948101 | 1.618 | 0.863 | E | 0 |
6539 | D | ASP | 94.73684211 | 1.359563616 | 1.056 | 0.734 | E | 0 |
6540 | Y | TYR | 93.81277622 | 1.333286719 | 1.185 | 1.608 | C | 0 |
6541 | K | LYS | 8.276416231 | -1.099039969 | 1.281 | 1.417 | C | 0 |
6542 | R | ARG | 37.00281237 | -0.282171213 | 1.35 | 1.571 | C | 0 |
6543 | D | ASP | 7.75411812 | -1.113892129 | 1.208 | 1.021 | E | 0 |
6544 | A | ALA | 9.642426677 | -1.060195861 | 1.106 | 0.879 | E | 0 |
6545 | P | PRO | 63.07754118 | 0.459294273 | 1.668 | 0.843 | E | 0 |
6546 | A | ALA | 8.557653676 | -1.091042653 | 2.535 | 1.049 | C | 0 |
6547 | H | HIS | 8.155885898 | -1.102467391 | 3.101 | 1.088 | C | 0 |
6548 | I | ILE | 2.531137003 | -1.262413721 | 2.73 | 1.671 | C | 0 |
6549 | S | SER | 12.4949779 | -0.979080222 | 1.459 | 1.021 | C | 0 |
6550 | T | THR | 99.15628767 | 1.485235732 | 1.132 | 0.777 | E | 0 |
6551 | I | ILE | 30.01205303 | -0.480961652 | 1.285 | 0.961 | C | 0 |
6552 | G | GLY | 39.45359582 | -0.212480312 | 1.842 | 0.834 | C | 0 |
6553 | V | VAL | 97.42868622 | 1.436109359 | 1.676 | 1.037 | C | 0 |
6554 | C | CYS | 94.49578144 | 1.352708773 | 1.775 | 0.964 | T | 0 |
6555 | S | SER | 6.227400562 | -1.157306132 | 1.851 | 1.454 | T | 0 |
6556 | M | MET | 8.396946565 | -1.095612548 | 1.914 | 1.945 | T | 0 |
6557 | T | THR | 99.15628767 | 1.485235732 | 1.199 | 0.948 | E | 0 |
6558 | D | ASP | 99.43752511 | 1.493233049 | 1.127 | 0.837 | E | 0 |
6559 | I | ILE | 46.64523905 | -0.007977505 | 1.246 | 1.541 | E | 0 |
6560 | A | ALA | 9.803133789 | -1.055625966 | 1.414 | 1.057 | C | 0 |
6561 | K | LYS | 8.838891121 | -1.083045336 | 1.431 | 2.077 | C | 0 |
6562 | K | LYS | 8.67818401 | -1.087615232 | 1.478 | 1.922 | C | 0 |
6563 | P | PRO | 9.200482121 | -1.072763072 | 1.403 | 1.007 | C | 0 |
6564 | T | THR | 8.396946565 | -1.095612548 | 1.524 | 1.339 | C | 0 |
6565 | E | GLU | 8.396946565 | -1.095612548 | 1.662 | 1.394 | C | 0 |
6566 | T | THR | 2.410606669 | -1.265841142 | 2.2 | 1.586 | G | 0 |
6567 | I | ILE | 2.450783447 | -1.264698668 | 2.528 | 1.678 | G | 0 |
6568 | C | CYS | 8.477300121 | -1.093327601 | 2.038 | 1.133 | G | 0 |
6569 | A | ALA | 2.490960225 | -1.263556194 | 1.68 | 1.074 | G | 0 |
6570 | P | PRO | 2.77219767 | -1.255558878 | 1.246 | 1.102 | C | 0 |
6571 | L | LEU | 42.34632382 | -0.1302222 | 1.385 | 1.108 | C | 0 |
6572 | T | THR | 10.08437123 | -1.047628649 | 1.659 | 0.799 | E | 0 |
6573 | V | VAL | 47.48895139 | 0.016014445 | 1.39 | 0.825 | E | 0 |
6574 | F | PHE | 2.571313781 | -1.261271247 | 1.097 | 0.723 | E | 0 |
6575 | F | PHE | 71.83607875 | 0.708353558 | 1.383 | 0.669 | E | 0 |
6576 | D | ASP | 99.43752511 | 1.493233049 | 1.456 | 0.891 | T | 0 |
6577 | G | GLY | 24.42748092 | -0.639765508 | 1.658 | 0.969 | T | 0 |
6578 | R | ARG | 62.51506629 | 0.44329964 | 1.664 | 1.75 | T | 0 |
6579 | V | VAL | 11.0486139 | -1.020209278 | 1.775 | 1.228 | T | 0 |
6580 | D | ASP | 2.531137003 | -1.262413721 | 2.126 | 1.642 | C | 0 |
6581 | G | GLY | 93.69224588 | 1.329859297 | 1.943 | 1.165 | H | 0 |
6582 | Q | GLN | 8.396946565 | -1.095612548 | 1.77 | 1.219 | H | 0 |
6583 | V | VAL | 8.316593009 | -1.097897496 | 1.731 | 1.374 | H | 1 |
6584 | D | ASP | 8.437123343 | -1.094470074 | 2.117 | 1.124 | H | 1 |
6585 | L | LEU | 8.11570912 | -1.103609865 | 1.808 | 1.264 | H | 0 |
6586 | F | PHE | 99.55805544 | 1.49666047 | 1.78 | 0.772 | H | 0 |
6587 | R | ARG | 11.16914423 | -1.016781857 | 2.16 | 1.482 | H | 0 |
6588 | N | ASN | 9.200482121 | -1.072763072 | 2.242 | 1.476 | C | 0 |
6589 | A | ALA | 29.04781037 | -0.508381023 | 1.716 | 1.057 | C | 0 |
6590 | R | ARG | 14.10204902 | -0.933381271 | 1.885 | 1.872 | C | 0 |
6591 | N | ASN | 92.76817999 | 1.3035824 | 1.553 | 0.822 | E | 0 |
6592 | G | GLY | 26.79791081 | -0.572359555 | 1.527 | 0.607 | E | 0 |
6593 | V | VAL | 82.6034552 | 1.014536533 | 1.337 | 0.792 | E | 0 |
6594 | L | LEU | 63.84089996 | 0.481001275 | 1.182 | 0.811 | E | 0 |
6595 | I | ILE | 50.22097228 | 0.093702662 | 1.147 | 0.872 | E | 0 |
6596 | T | THR | 12.81639213 | -0.969940432 | 1.387 | 0.88 | E | 0 |
6597 | E | GLU | 8.437123343 | -1.094470074 | 1.5 | 1.422 | C | 0 |
6598 | G | GLY | 8.557653676 | -1.091042653 | 1.644 | 1.178 | C | 0 |
6599 | S | SER | 8.597830454 | -1.089900179 | 1.06 | 1.369 | C | 0 |
6600 | V | VAL | 55.76536762 | 0.251364044 | 1.057 | 1.214 | C | 0 |
6601 | K | LYS | 97.22780233 | 1.43039699 | 2.137 | 2.478 | C | 0 |
6602 | G | GLY | 13.37886701 | -0.953945799 | 3.428 | 1.503 | C | 0 |
6603 | L | LEU | 23.58376858 | -0.663757457 | 2.947 | 1.355 | C | 0 |
6604 | Q | GLN | 2.732020892 | -1.256701352 | 3.052 | 2.113 | C | 0 |
6605 | P | PRO | 8.316593009 | -1.097897496 | 3.864 | 1.673 | C | 0 |
6606 | S | SER | 10.76737646 | -1.028206595 | 2.619 | 1.163 | E | 0 |
6607 | V | VAL | 18.20008035 | -0.816848945 | 1.925 | 1.3 | C | 0 |
6608 | G | GLY | 39.97589393 | -0.197628153 | 1.796 | 0.741 | C | 0 |
6609 | P | PRO | 43.02932905 | -0.110800145 | 1.551 | 0.86 | C | 0 |
6610 | K | LYS | 2.531137003 | -1.262413721 | 1.58 | 1.759 | C | 0 |
6611 | Q | GLN | 8.396946565 | -1.095612548 | 1.25 | 0.953 | C | 0 |
6612 | A | ALA | 39.81518682 | -0.202198048 | 1.043 | 0.896 | E | 0 |
6613 | S | SER | 9.843310566 | -1.054483492 | 1.141 | 0.89 | E | 0 |
6614 | L | LEU | 17.59742869 | -0.833986051 | 1.014 | 1.72 | E | 0 |
6615 | N | ASN | 53.19405384 | 0.178245722 | 1.349 | 1.61 | T | 0 |
6616 | G | GLY | 39.97589393 | -0.197628153 | 1.931 | 1.656 | T | 0 |
6617 | V | VAL | 23.34270791 | -0.6706123 | 1.305 | 1.631 | E | 0 |
6618 | T | THR | 12.8565689 | -0.968797958 | 0.941 | 1.08 | E | 0 |
6619 | L | LEU | 12.69586179 | -0.973367853 | 1.274 | 1.745 | E | 0 |
6620 | I | ILE | 8.276416231 | -1.099039969 | 1.187 | 1.183 | C | 0 |
6621 | G | GLY | 29.36922459 | -0.499241232 | 1.828 | 1.308 | C | 0 |
6622 | E | GLU | 8.316593009 | -1.097897496 | 2.459 | 2.859 | C | 0 |
6623 | A | ALA | 2.450783447 | -1.264698668 | 2.549 | 1.912 | C | 0 |
6624 | V | VAL | 50.42185617 | 0.099415031 | 2.365 | 1.853 | C | 0 |
6625 | K | LYS | 24.06588992 | -0.650047772 | 2.419 | 2.029 | C | 0 |
6626 | T | THR | 9.441542788 | -1.06590823 | 1.79 | 0.908 | C | 0 |
6627 | Q | GLN | 24.34712736 | -0.642050455 | 1.544 | 1.537 | C | 0 |
6628 | F | PHE | 9.160305344 | -1.073905546 | 1.507 | 0.835 | C | 0 |
6629 | N | ASN | 24.78907192 | -0.629483244 | 1.284 | 0.828 | E | 0 |
6630 | Y | TYR | 20.73121736 | -0.744873096 | 1.119 | 0.603 | E | 0 |
6631 | Y | TYR | 2.490960225 | -1.263556194 | 1.287 | 0.771 | E | 0 |
6632 | K | LYS | 8.67818401 | -1.087615232 | 1.46 | 0.923 | E | 0 |
6633 | K | LYS | 8.316593009 | -1.097897496 | 1.717 | 1.054 | E | 0 |
6634 | V | VAL | 47.04700683 | 0.003447233 | 1.984 | 1.193 | E | 0 |
6635 | D | ASP | 15.18682202 | -0.902534478 | 2.269 | 1.268 | T | 0 |
6636 | G | GLY | 78.06347931 | 0.885436995 | 2.261 | 1.024 | T | 0 |
6637 | V | VAL | 3.736440337 | -1.228139507 | 2.462 | 1.299 | E | 0 |
6638 | V | VAL | 2.531137003 | -1.262413721 | 1.892 | 1.101 | E | 0 |
6639 | Q | GLN | 10.88790679 | -1.024779173 | 1.935 | 1.397 | C | 0 |
6640 | Q | GLN | 9.562073122 | -1.062480808 | 1.124 | 1.781 | C | 0 |
6641 | L | LEU | 25.27119325 | -0.615773558 | 0.921 | 1.005 | C | 0 |
6642 | P | PRO | 48.33266372 | 0.040006394 | 1.094 | 0.928 | C | 0 |
6643 | E | GLU | 24.78907192 | -0.629483244 | 1.43 | 1.488 | C | 0 |
6644 | T | THR | 44.79710727 | -0.060531299 | 1.209 | 0.758 | C | 0 |
6645 | Y | TYR | 39.57412616 | -0.209052891 | 1.161 | 0.712 | C | 0 |
6646 | F | PHE | 48.93531539 | 0.057143501 | 1.161 | 0.715 | C | 0 |
6647 | T | THR | 98.192045 | 1.457816361 | 0.998 | 0.797 | C | 0 |
6648 | Q | GLN | 98.03133789 | 1.453246466 | 0.924 | 0.717 | C | 0 |
6649 | S | SER | 39.93571716 | -0.198770627 | 0.768 | 0.771 | C | 0 |
6650 | R | ARG | 99.87946967 | 1.50580026 | 0.926 | 0.668 | C | 0 |
6651 | N | ASN | 22.90076336 | -0.683179512 | 1.822 | 1.271 | T | 0 |
6652 | L | LEU | 17.59742869 | -0.833986051 | 1.138 | 1.161 | T | 0 |
6653 | Q | GLN | 4.740859783 | -1.199577663 | 1.764 | 1.458 | T | 0 |
6654 | E | GLU | 3.374849337 | -1.238421771 | 2.771 | 1.331 | T | 0 |
6655 | F | PHE | 99.91964644 | 1.506942734 | 1.287 | 0.815 | C | 0 |
6656 | K | LYS | 14.3029329 | -0.927668902 | 1.467 | 1.829 | C | 0 |
6657 | P | PRO | 87.06307754 | 1.141351123 | 1.194 | 0.876 | C | 0 |
6658 | R | ARG | 77.42065086 | 0.867157414 | 1.317 | 0.896 | C | 0 |
6659 | S | SER | 82.64363198 | 1.015679007 | 1.301 | 1.028 | H | 0 |
6660 | Q | GLN | 10.76737646 | -1.028206595 | 1.557 | 1.814 | H | 1 |
6661 | M | MET | 81.07673765 | 0.971122529 | 1.24 | 0.96 | H | 2 |
6662 | E | GLU | 99.87946967 | 1.50580026 | 1.124 | 0.725 | H | 2 |
6663 | I | ILE | 2.973081559 | -1.249846509 | 1.567 | 1.097 | H | 2 |
6664 | D | ASP | 98.23222178 | 1.458958835 | 1.582 | 0.909 | H | 2 |
6665 | F | PHE | 99.83929289 | 1.504657786 | 1.412 | 0.756 | H | 1 |
6666 | L | LEU | 84.53194054 | 1.069375274 | 1.64 | 1.179 | H | 0 |
6667 | E | GLU | 14.82523102 | -0.912816742 | 1.729 | 1.534 | H | 0 |
6668 | L | LEU | 26.11490558 | -0.591781609 | 1.583 | 1.202 | C | 1 |
6669 | A | ALA | 8.597830454 | -1.089900179 | 1.73 | 1.194 | H | 2 |
6670 | M | MET | 35.47609482 | -0.325585217 | 1.824 | 1.296 | H | 1 |
6671 | D | ASP | 41.14102049 | -0.164496413 | 1.822 | 1.367 | H | 1 |
6672 | E | GLU | 9.03977501 | -1.077332968 | 1.725 | 1.339 | H | 2 |
6673 | F | PHE | 99.87946967 | 1.50580026 | 1.566 | 0.839 | H | 2 |
6674 | I | ILE | 91.00040177 | 1.253313554 | 1.787 | 1.164 | H | 2 |
6675 | E | GLU | 18.80273202 | -0.799711838 | 1.94 | 1.374 | H | 2 |
6676 | R | ARG | 8.959421454 | -1.079617915 | 1.78 | 1.404 | H | 2 |
6677 | Y | TYR | 98.15186822 | 1.456673887 | 1.705 | 0.975 | H | 2 |
6678 | K | LYS | 9.120128566 | -1.07504802 | 1.751 | 1.749 | C | 1 |
6679 | L | LEU | 83.00522298 | 1.025961271 | 1.744 | 1.036 | T | 0 |
6680 | E | GLU | 75.7332262 | 0.819173515 | 1.937 | 1.789 | T | 0 |
6681 | G | GLY | 9.481719566 | -1.064765756 | 1.131 | 0.94 | T | 0 |
6682 | Y | TYR | 70.55042186 | 0.671794397 | 0.915 | 1.311 | T | 0 |
6683 | A | ALA | 42.3865006 | -0.129079726 | 1.089 | 0.928 | H | 0 |
6684 | F | PHE | 77.62153475 | 0.872869783 | 0.806 | 1.403 | H | 0 |
6685 | E | GLU | 81.63921254 | 0.987117162 | 1.118 | 1.317 | H | 0 |
6686 | H | HIS | 99.83929289 | 1.504657786 | 1.18 | 1.126 | H | 0 |
6687 | I | ILE | 46.00241061 | -0.026257085 | 0.918 | 1.071 | H | 0 |
6688 | V | VAL | 77.74206509 | 0.876297205 | 0.783 | 0.792 | H | 0 |
6689 | Y | TYR | 94.09401366 | 1.341284035 | 0.889 | 0.866 | C | 0 |
6690 | G | GLY | 99.91964644 | 1.506942734 | 0.955 | 0.695 | C | 0 |
6691 | D | ASP | 67.33627963 | 0.580396494 | 1.488 | 1.042 | C | 0 |
6692 | F | PHE | 42.06508638 | -0.138219516 | 1.605 | 1.813 | C | 1 |
6693 | S | SER | 66.93451185 | 0.568971757 | 1.66 | 1.37 | C | 1 |
6694 | H | HIS | 26.35596625 | -0.584926766 | 1.845 | 1.795 | C | 1 |
6695 | S | SER | 2.892728003 | -1.252131457 | 1.68 | 1.577 | C | 1 |
6696 | Q | GLN | 24.94977903 | -0.624913349 | 1.483 | 1.976 | C | 0 |
6697 | L | LEU | 73.84491764 | 0.765477248 | 1.314 | 1.451 | C | 0 |
6698 | G | GLY | 99.87946967 | 1.50580026 | 1.224 | 0.865 | C | 0 |
6699 | G | GLY | 99.91964644 | 1.506942734 | 0.827 | 0.754 | C | 0 |
6700 | L | LEU | 90.15668943 | 1.229321604 | 0.819 | 0.922 | C | 0 |
6701 | H | HIS | 99.87946967 | 1.50580026 | 0.808 | 0.892 | C | 0 |
6702 | L | LEU | 78.78666131 | 0.906001523 | 0.73 | 1.154 | C | 0 |
6703 | L | LEU | 76.97870631 | 0.854590203 | 0.757 | 0.828 | H | 0 |
6704 | I | ILE | 99.71876256 | 1.501230365 | 0.937 | 0.888 | H | 0 |
6705 | G | GLY | 58.3366814 | 0.324482367 | 1.147 | 0.601 | H | 0 |
6706 | L | LEU | 45.64081961 | -0.036539349 | 0.986 | 1.146 | H | 0 |
6707 | A | ALA | 10.36560868 | -1.039631333 | 0.806 | 0.886 | H | 0 |
6708 | K | LYS | 29.65046203 | -0.491243916 | 1.324 | 1.178 | H | 0 |
6709 | R | ARG | 24.30695058 | -0.643192929 | 1.158 | 0.823 | H | 0 |
6710 | F | PHE | 2.450783447 | -1.264698668 | 0.873 | 1.277 | H | 0 |
6711 | K | LYS | 17.71795902 | -0.83055863 | 1.413 | 1.979 | H | 0 |
6712 | E | GLU | 24.82924869 | -0.62834077 | 1.877 | 1.55 | C | 0 |
6713 | S | SER | 23.70429892 | -0.660330036 | 1.722 | 1.237 | C | 0 |
6714 | P | PRO | 7.794294898 | -1.112749655 | 1.785 | 1.515 | E | 0 |
6715 | F | PHE | 2.732020892 | -1.256701352 | 1.939 | 1.483 | E | 0 |
6716 | E | GLU | 3.013258337 | -1.248704035 | 1.877 | 1.712 | E | 0 |
6717 | L | LEU | 8.437123343 | -1.094470074 | 1.818 | 1.677 | E | 0 |
6718 | E | GLU | 56.40819606 | 0.269643625 | 2.091 | 1.553 | E | 0 |
6719 | D | ASP | 8.356769787 | -1.096755022 | 1.567 | 1.09 | E | 0 |
6720 | F | PHE | 23.50341503 | -0.666042405 | 1.604 | 1.362 | C | 0 |
6721 | I | ILE | 9.40136601 | -1.067050703 | 1.284 | 1.661 | C | 0 |
6722 | P | PRO | 9.441542788 | -1.06590823 | 0.953 | 1.137 | C | 0 |
6723 | M | MET | 8.11570912 | -1.103609865 | 0.835 | 1.3 | C | 0 |
6724 | D | ASP | 77.34029731 | 0.864872467 | 1.365 | 0.786 | C | 0 |
6725 | S | SER | 84.45158698 | 1.067090327 | 0.911 | 0.812 | C | 0 |
6726 | T | THR | 63.15789474 | 0.461579221 | 1.073 | 0.812 | C | 0 |
6727 | V | VAL | 27.28003214 | -0.558649869 | 0.718 | 0.988 | C | 0 |
6728 | K | LYS | 41.3017276 | -0.159926518 | 0.81 | 1.591 | C | 0 |
6729 | N | ASN | 25.5524307 | -0.607776242 | 1.072 | 1.187 | E | 0 |
6730 | Y | TYR | 41.34190438 | -0.158784044 | 1.395 | 0.906 | E | 0 |
6731 | F | PHE | 40.49819204 | -0.182775994 | 1.897 | 1.887 | E | 0 |
6732 | I | ILE | 45.27922861 | -0.046821613 | 1.728 | 1.1 | E | 1 |
6733 | T | THR | 77.34029731 | 0.864872467 | 1.839 | 1.512 | E | 2 |
6734 | D | ASP | 24.62836481 | -0.634053139 | 2.427 | 1.377 | E | 1 |
6735 | A | ALA | 51.02450783 | 0.116552138 | 2.583 | 1.832 | C | 0 |
6736 | Q | GLN | 8.236239454 | -1.100182443 | 2.684 | 2.09 | C | 0 |
6737 | T | THR | 26.35596625 | -0.584926766 | 2.184 | 1.588 | C | 0 |
6738 | G | GLY | 40.33748493 | -0.187345889 | 2.129 | 1.539 | E | 0 |
6739 | S | SER | 72.92085175 | 0.739200351 | 1.977 | 1.231 | E | 1 |
6740 | S | SER | 63.96143029 | 0.484428697 | 1.872 | 1.349 | E | 2 |
6741 | K | LYS | 99.67858578 | 1.500087891 | 2.083 | 1.333 | E | 1 |
6742 | C | CYS | 8.316593009 | -1.097897496 | 2.029 | 1.332 | C | 0 |
6743 | V | VAL | 99.55805544 | 1.49666047 | 1.671 | 1.441 | C | 0 |
6744 | C | CYS | 99.75893933 | 1.502372839 | 1.778 | 1.13 | E | 0 |
6745 | S | SER | 26.95861792 | -0.567789659 | 1.487 | 0.805 | C | 0 |
6746 | V | VAL | 62.3141824 | 0.437587271 | 0.65 | 0.817 | C | 0 |
6747 | I | ILE | 40.2169546 | -0.19077331 | 0.836 | 1.034 | C | 0 |
6748 | D | ASP | 99.87946967 | 1.50580026 | 0.912 | 0.581 | C | 0 |
6749 | L | LEU | 76.53676175 | 0.842022991 | 0.966 | 0.988 | C | 0 |
6750 | L | LEU | 81.55885898 | 0.984832214 | 1.137 | 1.324 | H | 0 |
6751 | L | LEU | 99.75893933 | 1.502372839 | 1.096 | 0.789 | H | 0 |
6752 | D | ASP | 99.67858578 | 1.500087891 | 1.229 | 1.054 | H | 0 |
6753 | D | ASP | 99.71876256 | 1.501230365 | 1.157 | 0.648 | H | 0 |
6754 | F | PHE | 95.21896344 | 1.373273301 | 0.833 | 0.705 | H | 0 |
6755 | V | VAL | 78.14383286 | 0.887721943 | 1.049 | 0.887 | H | 0 |
6756 | E | GLU | 25.03013258 | -0.622628401 | 1.441 | 1.033 | H | 0 |
6757 | I | ILE | 68.90317397 | 0.624952972 | 1.092 | 0.886 | H | 0 |
6758 | I | ILE | 16.87424669 | -0.854550579 | 1.243 | 1.25 | H | 0 |
6759 | K | LYS | 78.42507031 | 0.895719259 | 1.598 | 1.645 | H | 0 |
6760 | S | SER | 70.59059863 | 0.672936871 | 1.818 | 1.097 | H | 0 |
6761 | Q | GLN | 25.79349136 | -0.600921399 | 1.873 | 1.1 | C | 0 |
6762 | D | ASP | 63.92125352 | 0.483286223 | 2.515 | 1.442 | C | 0 |
6763 | L | LEU | 77.5411812 | 0.870584836 | 2.289 | 1.294 | C | 1 |
6764 | S | SER | 24.10606669 | -0.648905298 | 2.827 | 1.363 | C | 2 |
6765 | V | VAL | 63.64001607 | 0.475288906 | 2.588 | 1.394 | C | 2 |
6766 | V | VAL | 70.34953797 | 0.666082028 | 2.537 | 1.525 | E | 2 |
6767 | S | SER | 99.71876256 | 1.501230365 | 2.28 | 1.229 | E | 2 |
6768 | K | LYS | 99.43752511 | 1.493233049 | 2.212 | 1.402 | E | 2 |
6769 | V | VAL | 99.55805544 | 1.49666047 | 1.891 | 1.449 | E | 1 |
6770 | V | VAL | 62.47488951 | 0.442157166 | 1.788 | 1.042 | E | 0 |
6771 | K | LYS | 25.43190036 | -0.611203663 | 1.395 | 1.441 | E | 0 |
6772 | V | VAL | 95.98232222 | 1.394980303 | 1.048 | 1.221 | E | 0 |
6773 | T | THR | 8.597830454 | -1.089900179 | 1.105 | 0.779 | E | 0 |
6774 | I | ILE | 53.87705906 | 0.197667776 | 0.939 | 0.759 | E | 0 |
6775 | D | ASP | 99.79911611 | 1.503515313 | 1.072 | 0.557 | T | 0 |
6776 | Y | TYR | 25.27119325 | -0.615773558 | 1.109 | 0.659 | T | 0 |
6777 | T | THR | 19.52591402 | -0.77914731 | 1.359 | 1.009 | E | 0 |
6778 | E | GLU | 8.437123343 | -1.094470074 | 0.993 | 1.082 | E | 0 |
6779 | I | ILE | 44.11410205 | -0.079953353 | 0.776 | 0.963 | E | 0 |
6780 | S | SER | 8.758537565 | -1.085330284 | 1.303 | 1.04 | E | 0 |
6781 | F | PHE | 63.15789474 | 0.461579221 | 1.516 | 0.716 | E | 0 |
6782 | M | MET | 99.55805544 | 1.49666047 | 1.94 | 1.291 | E | 0 |
6783 | L | LEU | 83.00522298 | 1.025961271 | 1.917 | 1.043 | E | 1 |
6784 | W | TRP | 99.83929289 | 1.504657786 | 2.241 | 1.683 | E | 2 |
6785 | C | CYS | 78.30453998 | 0.892291838 | 2.443 | 1.081 | E | 2 |
6786 | K | LYS | 58.17597429 | 0.319912471 | 2.319 | 1.968 | E | 2 |
6787 | D | ASP | 77.66171153 | 0.874012257 | 2.399 | 1.607 | T | 2 |
6788 | G | GLY | 42.58738449 | -0.123367357 | 2.381 | 1.297 | T | 2 |
6789 | H | HIS | 12.17356368 | -0.988220012 | 2.277 | 1.568 | E | 2 |
6790 | V | VAL | 51.50662917 | 0.130261823 | 2.125 | 1.103 | E | 2 |
6791 | E | GLU | 8.396946565 | -1.095612548 | 2.152 | 1.308 | E | 1 |
6792 | T | THR | 99.71876256 | 1.501230365 | 1.933 | 1.276 | E | 0 |
6793 | F | PHE | 78.6259542 | 0.901431628 | 1.58 | 0.838 | E | 0 |
6794 | Y | TYR | 99.638409 | 1.498945418 | 1.395 | 0.968 | E | 0 |
6795 | P | PRO | 99.55805544 | 1.49666047 | 1.385 | 0.966 | E | 0 |
6796 | K | LYS | 10.08437123 | -1.047628649 | 2.385 | 2.563 | C | 0 |
6797 | L | LEU | 97.70992366 | 1.444106676 | 4.239 | 3.405 | C | 0 |
6798 | Q | GLN | 99.638409 | 1.498945418 | 6.687 | 6.048 | C | 0 |
2. I-TASSER server for protein structure and function prediction [Internet]. [cited 2020 Apr 12];Available from: https://zhanglab.ccmb.med.umich.edu/I-TASSER/
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