* Denotes first (or co-first) or corresponding author position

! Denotes mentored student as first author

85. Zhang X, Moore C, Harmacek L, Domenico J, Rangaraj V, Ideozu JE, Knapp JR, Woods KA, Jump S, Jia S, Prokop JW, Bowler R, Hessner MJ, Gelfand EW, Levy H. CFTR-mediated monocyte-macrophage dysfunction revealed by cystic fibrosis proband-parent comparisons. JCI Insights. Accepted (2022). PMID:. IMPACT FACTOR: 8.3
84. Teoh ST, Leimanis-Laurens ML, Comstock SS, Winters JW, Vandenbosch NL, Prokop JW, Bachmann AS, Lunt SY, Rajasekaran S. Combined plasma and urinary metabolomics uncover metabolic perturbations associated with severe respiratory syncytial viral infection and future development of asthma in infant patients. Metabolites. Accepted (2022). PMID:. IMPACT FACTOR: 4.75
83. Song NJ, Lee A, Yasmeen R, Shen Q, Yang K, Kumar SB, Muhanna D, Arnipalli S, Noria SF, Needleman BJ, Hazey JW, Mikami DJ, Prokop JW, Ziozenkova O. Epiregulin as an alternative ligand for leptin receptor alleviates glucose intolerance without change in obesity. Cells. Accepted (2022). PMID:. IMPACT FACTOR: 4.33
82. Russell MM, Leimanis-Laurens ML, Bu S, Kinney GA, Teoh ST, McGee RL, Ferguson K, Winters JW, Lunt SY, Prokop JW, Rajasekaran S, Comstock SS. Loss of Health Promoting Bacteria in the Gastrointestinal Microbiome of PICU Infants with Bronchiolitis: A Single-Center Feasibility Study. Children. Accepted (2022). PMID:. IMPACT FACTOR: 2.08
*81. Prokop JW, Jdanov V, Savage L, Morris M, Lamb N, VanSickle E, Stenger CL, Rajasekaran S, Bupp CP. Computational and experimental analysis of genetic variants. Comprehensive Physiology. Accepted (2022). PMID:. IMPACT FACTOR: 9.1
*!80. Charron JG, Hernandez A, Bilinovich SM, Vogt DL, Bedinger LA, Seaver LH, Williams M, Devries S, Campbell DB, Bupp CP, Prokop JW. NMDA receptor genetics: The power of paralog homology and protein dynamics in defining dominant vs recessive genetics. American Journal of Medical Genetics part A. 188(2):556-568 (2022). PMID: 34726335. IMPACT FACTOR: 2.3

*!79. Bauss J, Morris M, Shankar R, Olivero R, Buck LN, Stenger CL, Hinds D, Mills J, Eby A, Zagorski JW, Smith C, Cline S, Hartog N, Chen B, Huss J, Carcillo JA, Rajasekaran S, Bupp C, Prokop JW. CCR5 and biological complexity: the need for data integration and educational materials to normalize genetic/biological reductionism at the interface of Ethical, Legal, and Social Implications. Frontiers in Immunology. 12:790041 (2021). PMID: 34925370 IMPACT FACTOR: 7.5
78. Bilinovich SM, Morris DL, Prokop JW, Caporoso JA, Taraboletti A, Duangjumpa N, Panzner MJ, Shriver LP, Leeper TC. Binding to Bacterial Glutaredoxins Observed by NMR. Biophysica. 1(4), 359-376 (2021).
77. Yu W, Haque I, Venkatraman A, Menden HL, Mabry S, Roy B, Xia S, Prokop JW, Umar S, Geurts AM, Sampath V. SIGIRR mutation identified in human necrotizing enterocolitis (NEC) disrupts STAT3-dependent microRNA expression in neonatal gut. Cellular and Molecular Gastroenterology and Hepatology. S2352-345X(21)00197-1 (2021). PMID: 34563711. IMPACT FACTOR: 7.076
76. Blair B, Stenger C, Painter J, Prokop JW, Woodley S, Ridlen J, Watkins R. Two Variants of SLC6A1 on Amino Acid 451 (D451E AND D451G) Associated with Developmental Delay and Epilepsy. The Journal of the Alabama Academy of Science. 91(2021).
75. VanSickle EA, Michael J, Bachmann AS, Rajasekaran S, Prokop JW, Kuzniecky R, Hofstede FC, Steindl K, Rauch A, Lipson MH, Bupp CP. Expanding the Phenotype – Four new cases and hope for treatment in Bachmann-Bupp Syndrome. American Journal of Medical Genetics part A. 185(11):3485-3493 (2021). PMID: 34477286. IMPACT FACTOR: 2.3
*74. Prokop JW, Bupp CP, Chesla D, Faber W, Love CP, Karam R, Abualkheir N, Feldmann B, Teng L, McBride T, Leimanis ML, English BK, Frisch A, Bauss J, Kalpage N, Derbedrossian A, Pinti RM, Hall N, Mills J, Eby A, VanSickle EA, Pageau SC, Shankar R, Chen B, Carcillo J, Olivero R, Hartog NL, Rajasekaran S. High-Density Blood Transcriptomics Reveals Precision Immune Signatures of SARS-CoV-2 Infection in Hospitalized Individuals. Frontiers in Immunology. 12:694243 (2021). PMID: 34335605. IMPACT FACTOR: 7.5
73. Rajasekaran S, Bupp CP, Leimanis M, Shukla A, Russell C, Junewick J, Gleason E, VanSickle EA, Edgerly Y, Wittman B, Prokop JW, Bachmann AS. Repurposing Eflornithine to Treat a Patient with a Rare ODC1 Gain of Function Variant Disease. eLife. 10:e67097 (2021). PMID: 34282722. IMPACT FACTOR: 7.08
!72. Ngo J, Prokop JW, Umfleet J, Seaver LH. Perinatal manifestations of DARS2-associated leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL). Child Neurology Open. 8:2329048X211019173 (2021). PMID: 34104671. IMPACT FACTOR:
71. Leimanis-Laurens M, Wolfrum E, Ferguson K, Grunwell JR, Sanfilippo D, Prokop JW, Lydic TA, Rajasekaran S. Hexosylceramides and glycerophosphatidylcholine GPC(36:1) increase in Multi-Organ Dysfunction Syndrome patients with Pediatric Intensive Care Unit Admission over 8-day hospitalization. Journal of Personalized Medicine. 11(5):339 (2021). PMID: 33923179. IMPACT FACTOR: 4.43
*!70. Gupta R, Leimanis ML, Adams M, Bachmann AS, Uhl K, Bupp CP, Hartog NL, Kort EJ, Olivero R, Comstock SS, Sanfilippo DJ, Lunt SY, Prokop JW*, Rajasekaran S*. Balancing Precision vs. Cohort Transcriptomic Analysis of Acute and Recovery Phase of Viral Bronchiolitis. American Journal of Physiology-Lung Cellular and Molecular Physiology. 320(6):L1147-L1157 (2021). *Co-corresponding. PMID: 33851876. IMPACT FACTOR: 4.41
*69. Hartog N, Faber W, Frisch A, Bauss J, Bupp CP, Rajasekaran S, Prokop JW. SARS-CoV-2 infection: molecular mechanisms of severe outcomes to suggest therapeutics. Expert Review of Proteomics. 18(2):105-118 (2021). PMID: 33779460. IMPACT FACTOR: 3.80
*68. Prokop JW, Bupp CP, Frisch A, Bilinovich SM, Campbell DB, Vogt D, Schultz CR, Uhl KL, VanSickle E, Rajasekaran S, Bachmann AS. Emerging Role of ODC1 in Neurodevelopmental Disorders and Brain Development. Genes. 12(4):470 (2021). PMID: 33806076. IMPACT FACTOR: 2.98
67. Peng H, Cassel J, McCracken D, Prokop JW, Sementino E, Cheung M, Collop PR, Polo A, Joshi S, Mandell JP, Ayyanathan K, Hinds D, Mallkowicz SB, Harbour JW, Bowcock AM, Salvino J, Kennedy E, Testa JR, Rauscher FJ III. Kinetics characterization of ASXL1/2-mediated allosteric regulation of BAP1 deubiquitinase. Molecular Cancer Research. 19(7):1099-1112. (2021). PMID: 33731362. IMPACT FACTOR: 4.63
66. Leimanis-Laurens M, Ferguson K, Wolfrum E, Boville B, Sanfilippo D, Lydic T, Prokop JW, Rajasekaran S. Pediatric Multi-Organ Dysfunction Syndrome: Analysis by an Untargeted “Shotgun” Lipidomic Approach Reveals Low-abundance Plasma Phospholipids and Dynamic Recovery Over 8-Day Period, a Single-Center Observational Study. Nutrients. 13(3):774. (2021). PMID: 33673500 IMPACT FACTOR: 4.546
65. Hartog NL, Davis, AT, Prokop JW, Walls A, Rajasekaran. Monitoring Neutrophil to Lymphocyte Ratio in COVID-19 Patients Receiving Tocilizumab. Annals of Allergy, Asthma & Immunology. 126(3):306-308. (2021). PMID: 33387615. IMPACT FACTOR: 3.56
64. Leimanis-Laurens M, Gil D, Kampfschulte A, Krohn C, Prentice E, Sanfilippo D, Prokop JW, Lydic T, Rajasekaran S. The Feasibility of Studying Metabolites in PICU Multi-Organ Dysfunction Syndrome Patients Over an 8-day Course Using An Untargeted Approach. Children. 8(2), 151 (2021). PMID: 33670443. IMPACT FACTOR: 2.08
*63. Keele GR*, Prokop JW*, He H, Holl K, Littrell J, Deal A, Kim Y, Kyle PB, Attipoe E, Johnson AC, Uhl KL, Sirpilla OL, Jahanbakhsh S, Robinson M, Levy S, Valdar W, Garrett MR, Solberg Woods LC. Sept8/SEPTIN8 involvement in cellular structure and kidney damage is identified by genetic mapping and a novel human tubule hypoxic model. Scientific Reports. 11(1):2071 (2021). *Co-first. PMID: 33483609. IMPACT FACTOR: 4.00
*!62. Sanders M, Lawlor JMJ, Li X, Schuen JN, Millard SL, Zhang X, Buck L, Grysko B, Uhl KL, Hinds D, Stenger CL, Morris M, Lamb N, Levy H, Bupp C, Prokop JW. Genomic, Transcriptomic, and Protein Landscape Profile of CFTR and Cystic Fibrosis. Human Genetics 140:423-439 (2021). PMID: 32734384. IMPACT FACTOR: 3.93

*61. Bilinovich SM, Uhl KL, Lewis K, Soehnlen X, Williams M, Vogt D, Prokop JW*, Campbell DB*. Integrated RNA Sequencing Reveals Epigenetic Impacts of Diesel Particulate Matter Exposure in Human Cerebral Organoids. Developmental Neuroscience. 42(5-6):195-207. (2020). *Co-corresponding. PMID: 33657557. IMPACT FACTOR: 2.03
!60. Afrin A, Prokop JW, Underwood A, Uhl KL, VanSickle AE, Baruwal R, Wajda M, Rajasekaran S, Bupp C. NAA10 Variant in 38-Week Gestation Male Patient: A Case Study. CSHL Molecular Case Studies (2020). 6(6):a005868. PMID: 33335012. IMPACT FACTOR: 1.8
59. Shankar R, Leimanis M, Newbury PA, Liu K, Xing J, Nedveck D, Kort EJ, Prokop JW, Zhou G, Bachmann AS, Chen B, Rajasekaran S. Gene expression signatures identify pediatric patients with multiple organ dysfunction who require advanced life support in the intensive care unit. EBiomEdicine. 62:103122 (2020). PMID: 33248372. IMPACT FACTOR: 5.7
!58. Savage LT, Adams SD, James KN, Chowdhury S, Rajasekaran S, Prokop JW, Bupp C. Rapid whole genome sequencing identifies a homozygous novel variant, His540Arg, in HSD17B4 resulting in D-bifunctional protein deficiency disorder diagnosis. CSHL Molecular Case Studies (2020). 6(6):a005496. PMID: 33115767. IMPACT FACTOR: 1.8
57. Bilinovich SM, Lewis K, Thompson BL, Prokop JW, Campbell D. Environmental epigenetics of diesel particulate matter toxicogenomics. International Journal of Environmental Research and Public Health. 17, 7386. (2020). PMID: 33050454. IMPACT FACTOR: 2.85
56. Wundrach D, Martinetti LE, Stafford AM, Bilinovich SM, Angara K, Prokop JW, Crandall SR, Vogt D. A human TSC1 variant screening platform in GABAergic cortical interneurons for Genotype to Phenotype assessments. Frontiers In Molecular Neuroscience (2020). 13:573409. PMID: 33071758. IMPACT FACTOR: 5.08
*!55. Sirpilla O, Bauss J, Gupta R, Underwood A, Qutob D, Freeland T, Bupp C, Carcillo J, Hartog N, Rajasekaran S, Prokop JW. SARS-CoV-2 encoded proteome and human genetics: from interaction-based to ribosomal biology impact on disease and risk processes. Journal of Proteome Research (2020). 19(11):4275-4290. PMID 32686937. IMPACT FACTOR: 4.3
54. Graff EC, Cochran JN, Kaelin CB, Day K, Gray-Edwards HL, Watanabe R, Koehler JW, Falgoust RA, Prokop JW, Myers RM, Cox NR, Barsh GS, Martin DR. PEA15 loss of function and defective cerebral development in the domestic cat. PLOS Genetics (2020). 16(12):e1008671. PMID 33290415. IMPACT FACTOR: 5.5
53. Millstead J, Kamat A, Duffner U, Abdel-Mageed A, Freswick Peter, Dickens D, Stumph J, Prokop JW, Hartog NL. WD Repeat Domain 1 (WDR1) Deficiency Presenting as a Cause of Infantile Inflammatory Bowel Disease. Journal of Pediatric Gastroenterology and Nutrition (2020). 71(4):e113-e117. PMID: 32960541. IMPACT FACTOR: 2.8
*!52. Gupta R, Charron J, Stenger CL, Painter J, Steward H, Cook TW, Faber W, Frisch A, Lind E, Bauss J, Li X, Sirpilla O, Soehnlen X, Underwood A, Hinds D, Morris M, Lamb N, Carcillo JA, Bupp C, Uhal BD, Rajasekaran S, Prokop JW. SARS-CoV-2 (COVID-19) structural and evolutionary dynamicome: insights into functional evolution and human genomics. JBC (2020). 14;295(33):11742-11753. PMID 32587094. IMPACT FACTOR: 4.1
51. Devries S, Mulder M, Charron JG, Prokop JW, Mark PR. SLC6A1 G443D associated with developmental delay and epilepsy. CSHL Molecular Case Studies (2020). 25;6(4):a005371. PMID:32660967. IMPACT FACTOR: 1.8
*50. Prokop JW, Shankar R, Gupta R, Leimanis ML, Nedveck D, Uhl K, Chen B, Hartog NL, Van Veen J, Sisco JS, Sirpilla O, Lydic T, Boville B, Hernandez A, Braunreiter C, Kuk CC, Singh V, Mills J, Wegener M, Adams M, Rhodes M, Bachmann AS, Pan W, Byrne-Steele ML, Smith DC, Depinet M, Brown BE, Eisenhower M, Han J, Haw M, Madura C, Sanfilippo DJ, Seaver LH, Bupp C, Rajasekaran S. Virus-induced genetics revealed by multidimensional precision medicine transcriptional workflow applicable to COVID-19.
49. Partridge EC, Chhetri SB, Prokop JW, Ramaker R, Jansen CS, Goh ST, Mackiewicz M, Newberry KM, Brandsmeier LA, Dean EC, Jiang S, Savic D, Wold BJ, Mortazavi A, Myers RM, Mendenhall EM. Occupancy patterns of 208 DNA-associated proteins in a single human cell type. Nature (2020) 583:720-728. PMID: 32728244. IMPACT FACTOR: 43.07
*48. JW Prokop, Chhetri SB, van Veen JE, Chen X, Underwood AC, Uhl K, Dwinell MR, Geurts AM, Correa S, Arnold AP. Transcriptional analysis of the multiple Sry genes and developmental program at the onset of testis differentiation in the rat. Biology of Sex Differences (2020) 11:28. PMID: 32398044. IMPACT FACTOR: 3.19
47. MacKay CI, Bick D, Prokop JW, Munoz I, Rouse J, Downs J, Leonard H. Expanding the phenotype of the CDKL5 deficiency disorder: are seizures mandatory? American Journal of Medical Genetics Part A (2020). 182(5):1217-1222. PMID: 32034940. IMPACT FACTOR: 2.3
46. Fan F, Geurts AM, Pabbidi MR, Ge Y, Zhang C, Wang S, Liu Y, Gao W, Li L, He X, Lv W, Muroya Y, Hirata T, Prokop J, Booz GW, Jacob HJ, Roman RJ. A Mutation in Gamma-Adducin Impairs Autoregulation of Renal Blood Flow and Promotes the Development of Renal Disease. Journal of the American Society of Nephrology (2020) 31(4):687-700. PMID: 32029431. IMPACT FACTOR: 8.98

45. Cochran JN, McKinley EC, Cochran M, Amaral MD, Moyers BA, Lasseigne BN, Gray DE, Lawlor JMJ, Prokop JW, Geier EG, Holt JM, Thompson ML, Newberry JS, Yokoyama JS, Worthey EA, Geldmacher DS, Love MN, Cooper GM, Myers RM, Roberson ED. Genome sequencing for early-onset or atypical dementia: high diagnostic yield and frequent observation of multiple contributory alleles. Cold Spring Harbor Molecular Case Studies (2019) 5(6). PMID: 31836585. IMPACT FACTOR: 1.8
*!44. Shepard CJ, Cline SG, Hinds D, Jahanbakhsh S, Worthey E, Prokop JW. Breakdown of Multiple Sclerosis Genetics to Identify an Integrated Disease Network. Physiological Genomics (2019) 51(11)562-577. PMID: 31482761. IMPACT FACTOR: 2.6
43. Nissim S, Leshnicher I, Mancias JD, Greenblatt MB, Maertens O, Cox AG, Hedgepeth J, Kim AJ, Wucherpfennig J, Gonyo P, Brandt A, Lorimer E, Prokop JW, Heidel JR, Wang XX, Harper JW, Cichowski K, Kimmelman AC, Houvras Y, Syngal S, Williams C, Goessling W. A germline mutation in RABL3 alters KRAS prenylation and is associated with hereditary cancer susceptibility. Nature Genetics (2019) 51(9):1308-1314. PMID: 31406347. IMPACT FACTOR: 27.9
42. Plasterer C, Tsaih SW, Peck AR, Chervoneva I, O’Meara C, Sun Y, Lemke A, Murphy D, Smith J, Ran S, Kovatich AJ, Hooke J, Shriver CD, Hu H, Mitchell EP, Bergom C, Joshi A, Auer P, Prokop JW, Rui H, Flister M. Neuronatin is a modifier of estrogen receptor-positive breast cancer incidence and outcome. Breast Cancer Research and Treatment. 177(1):77-91 (2019). PMID: 31165373. IMPACT FACTOR: 3.9
41. Hiatt SM, Thompson ML, Prokop JW, Lawlor JMJ, Gray DE, Bebin EM, Rinne R, Kempers M, Mignot C, Nava C, Depienne C, Pfundt R, Bon B, Kalsner L, Rauch A, Joset P, Bachmann-Gagescu R, Wentzensen IM, McWalter K, Cooper GM. Deleterious Variation in BRSK2 Associates with a Neurodevelopmental Disorder. American Journal of Human Genetics. 104(4):701-708 (2019). PMID 30879638. IMPACT FACTOR: 9.0
*40. Cline S, Prokop JW. Framework, barriers, and proposed solutions for engaging students in bioinformatic research. Proceedings of the 2018 International Conference on Bioinformatics & Computational Biology. (2019) 42-46. IMPACT FACTOR: N/A
39. Patel N, Wang J, Shiozawa K, Jones KB, Zhang Y, Prokop JW, Davenport GG, Nihira NT, Hao Z, Wong D, Brandsmeier L, Meadows S, Sampaio AV, Werff RV, Endo M, Capecchi M, McNagny K, Mak T, Nielsen TO, Underhill TM, Myers RM, Kondo T, Su L. HDAC2 regulates site-specific acetylation of MDM2 and its ubiquitination signaling in tumor suppression. iScience. 13:43-54 (2019). PMID: 30818224. IMPACT FACTOR: 4.4
!38. Korakavi N, Prokop JW, Seaver L. Evolution of the Phenotype of Craniosynostosis with Dental Anomalies Syndrome and Report of IL11RA Variant Population Frequencies in a Crouzon-Like Autosomal Recessive Syndrome. American Journal of Medical Genetics Part A. 179(4):668-673 (2019). PMID: 30811827. IMPACT FACTOR: 2.3

37. Hiatt SM, Neu MB, Hardigan A, Ramaker R, Prokop JW, Prchal J, Hancarova M, Prchalova D, Havlovicova M, Stranecky V, Yim D, Powis Z, Keren B, Nava C, Mignot C, Rio M, Revah-Politi A, Hemati P, Strong N, Iglesias AD, Suchy S, Willaert R, Wentzensen IM, Wheeler PG. Hurst ACE, Wheless JW, Lacassie Y, Sedlacek Z, Cooper GM. De novo mutations in the GTP/GDP-binding region of RALA, a RAS-like small GTPase, cause intellectual disability and developmental delay. PLOS Genetics. 14(11):e1007671 (2018). PMID: 30500825. IMPACT FACTOR: 6.1
36. Seaver LH, DeRoss S, Anderson NJ, Betz B, Prokop JW, Lannen N, Jordan R, Rajasekaran S. Lethal NARS2-related disorder associated rapidly progressive intractable epilepsy and global brain atrophy. Pediatric Neurology. S0887-8994(18):30499 (2018). PMID: 30327238. IMPACT FACTOR: 2.3
35. Blok LS, Hiatt SM, Bowling KM, Prokop JW, Engel KL, Cochran JN, Bebin EM, Bijlsma E, Terhal P, Smith R, Hurst J, Cho M, Wangler M, Streff H, Symonds J, Zuberi S, Sanders V, Simon M, Pfundt R, Brunner HG, Fisher SE, Kleefstra T, Cooper GM. De novo mutations in MED13, a component of the Mediator complex, cause a new neurodevelopmental disorder. Human Genetics. 137(5):375-388 (2018). PMID: 29740699. IMPACT FACTOR: 3.5
*34. Prokop JW, May T, Strong K, Bilinovich SM, Bupp C, Rajasekaran S, Worthey EA, Lazar J. Whole genome sequencing in the clinic: The past, present, and future of genomic medicine. Physiological Genomics. 50(8):563-579 (2018). PMID:29727589. IMPACT FACTOR: 2.6
33. Fontaine F, Foodall S, Prokop J, Howard C, Moustaqil M, Kumble S, Rasicci S, Osborne G, Gambin Y, Sierecki E, Jones M, Zuegg J, Mahler S, Francois M. Functional domain analysis of SOX18 transcription factor using a scFv-fragment based approach. mAbs. 10(4):596-606 (2018). PMID:29648920. IMPACT FACTOR: 4.4
*32. Prokop JW, Yeo NC, Ottmann C, Chhetri SB, Florus KL, Ross EJ, Sosonkina N, Link BA, Freedman BI, Coppola CJ, McDermott-Roe C, Leysen S, Milroy L, Meijer FA, Geurts AM, Rauscher FJ, Ramaker R, Flister MJ, Jacob HJ, Mendenhall EM, Lazar J. Characterization of Coding/Noncoding Variants for SHROOM3 in Patients with CKD. Journal of the American Society of Nephrology. 29(5):1525-1535 (2018). PMID: 29476007. IMPACT FACTOR: 8.98
31. Peng H, Prokop J, Karar J, Park K, Cao L, Harbour J, Bowcock AM, Malkowicz SB, Cheung M, Testa JR, Rauscher FJ III. Familial and somatic BAP1 mutations inactivate ASXL1/2-mediated allosteric regulation of BAP1 deubiquitinase by Targeting multiple independent domains. Cancer Research. 78(5):1200-1213 (2018). PMID: 29284740. IMPACT FACTOR: 9.3
30. Keele GR, Prokop JW, He H, Holl K, Littrell J, Deal A, Francic S, Cui L, Gatti DM, Broman KW, Tschannen M, Tsaih SW, Zagloul M, Kim Y, Baur B, Fox J, Robinson M, Levy S, Flister MJ, Mott R, Valdar W, Solberg-Woods LC. Genetic fine-mapping and identification of candidate genes and variants for adiposity traits in outbred rats. Obesity. 26(1):213-222 (2018). PMID 29193816. IMPACT FACTOR: 3.97

29. Schilter K, Steiner J, Demos W, Maheshawri M, Prokop JW, Worthey E, Drolet B, Siegel DH. RNF213 variants in a child with Segmental Hemangioma Syndrome and Motamoya Vasculopathy. American Journal of Medical Genetics: Part A. 173(9):2557-2561 (2017). PMID 28686325. IMPACT FACTOR: 2.3
28. Londraville RL, Prokop JW, Liu Q, Duff RJ, Tuttle M. On the Molecular Evolution of Leptin, Leptin Receptor, and Endospanin. Frontiers in Endocrinology. 8:58 (2017). PMID 28443063. IMPACT FACTOR: 3.68
*27. Prokop JW, Lazar J, Crapitto G, Smith DC, Worthey EA, Jacob HJ. Molecular modeling in the age of clinical genomics, the enterprise of the next generation. Journal of Molecular Modeling. 23: 75 (2017). PMID 28204942. IMPACT FACTOR: 1.34
26. Cramer JM, Pohlman D, Gomez F, Mark L, Lornegay B, Hall C, Buchwald WA, Walavalkar NM, Bilinovich SM, Prokop JW, Hill AL, Williams Jr DC. Methylation specific targeting of a chromatin remodeling complex from sponges to humans. Scientific Reports. 7:40674 (2017). PMID: 28094816. IMPACT FACTOR: 4.01
25. Ball HC, Londraville RL, Prokop JW, George JC, Suydam R, Thewissen JGM, Duff RJ. Beyond Thermoregulation: Metabolic Function of Cetacean Blubber in Migrating Bowhead and Beluga Whales. Journal of Comparative Physiology B. 187:235-252 (2017). PMID: 27573204. IMPACT FACTOR: 2.34

24. Wilson JM, Prokop JW, Lorimer E, Ntantie E, Williams CL. Differences in the phosphorylation-dependent regulation of prenylation of Rap1A and Rap1B. Journal of Molecular Biology. 428:4929-4945 (2016). PMID: 27760305. IMPACT FACTOR: 4.63
23. Moller RS, Weckhuysen S, Chipaux M, Marsan E, Taly V, Beben EM, Hiatt SM, Prokop JW, Bowling KM, Mei D, Conti V, Frange P, Ferrand-Sorbets S, Dorgmuller G, Lambrecq V, Larsen LHG, Leguern E, Guerrini R, Rubboli G, Cooper GM, Baulac S. Germline and somatic mutations in the MTOR gene in focal cortical dysplasia and epilepsy. Neurology: Genetics, 2:e118 (2016). PMID 27830187. IMPACT FACTOR: 3.65
22. Bergom C, Hauser AD, Rymaszewski A, Gonyo P, Prokop JW, Jennings BC, Lawton AJ, Frei A, Lorimer EL, Aguilera-Barrantes I, Mackinnon AC, Noon K, Fierke CA, Williams CL. The tumor suppressive small GTPase DiRas1 binds the non-canonical guanine nucleotide exchange factor SmgGDS and antagonizes SmgGDS interactions with oncogenic small GTPases. Journal of Biological Chemistry, 291(12):6534-6545 (2016). PMID: 27197236. IMPACT FACTOR: 4.13
*21. Prokop JW, Tsaih SW, Faber AB, Boehme S, Underwood AC, Troyer S, Playl L, Milsted A, Turner ME, Ely D, Martins AS, Tutaj M, Lazar J, Dwinell MR, Jacob HJ. The Phenotypic Impact of the Male Specific Region of Chromosome-Y in Inbred Mating: The role of genetic variants and gene duplications in multiple inbred rat strains. Biology of Sex Differences, 7:10 (2016). PMID: 26848384. IMPACT FACTOR: 3.19

*20. Prokop JW, Deschepper CF. Chromosome Y genetic variants: impact in animal models and on human disease. Physiological Genomics, 47(11):525-537 (2015). PMID: 26286457. IMPACT FACTOR: 2.6
19. Flister MJ, Prokop JW, Dwinell M, Lazar J, Geurts A. 2015 Guildelines for Establishing Rat Transgenic Models for Cardiovascular Research. Journal of Cardiovascular Translational Research, 8(4):269-277 (2015). PMID: 25920443. IMPACT FACTOR: 2.76
*18. Prokop JW, Petri V, Shimoyama ME, Watanabe IKM, Caserini DE, Leeper TC, Bilinovich SM, Jacob HJ, Santos RA, Martins AS, Araujo FC, Reis FM, Milsted A. Structural libraries of protein models for multiple species to understand evolution of the renin-angiotensin system. General and Comparative Endocrinology, 215:106-116 (2015). PMID: 25260253. IMPACT FACTOR: 2.45
*17. Araujo FC, Milsted A, Watanabe IKM, Del Puerto HL, Santos RAS, Lazar J, Reis FM, Prokop JW. Similarities and differences of X and Y chromosome homologous genes, SRY and SOX3, in regulating the renin-angiotensin system promoters. Physiological Genomics, 47:177-186 (2015). PMID: 25759379. IMPACT FACTOR: 2.6
16. Rudemiller NP, Lund H, Priestley JR, Prokop JW, Jacob HJ, Geurts AM, Mattson DL. Mutation of SH2B3 (LNK), a GWAS candidate for hypertension, attenuates Dahl SS hypertension via inflammatory modulation. Hypertension, 65:1111-1117 (2015). PMID: 25776069. IMPACT FACTOR: 7.02
15. Chang AT, Liu Y, Ayyanathan K, Benner C, Jiang Y, Prokop JW, Paz H, Wang D, Li H, Fu X, Rauscher FJ, Yang J. An evolutionarily conserved DNA architecture determines target specificity of Twist family bHLH transcription factors. Genes and Development, 29:603-616 (2015). PMID: 25762439. IMPACT FACTOR: 9.41
14. Prisco SZ, Prokop JW, Sarkis AB, Yeo NC, Hoffman MJ, Hansen CC, Jacob HJ, Flister MJ, Lazar J. Refined mapping of a hypertension susceptibility locus on rat chromosome 12. Hypertension, 64:883-890 (2014). PMID: 25001272. IMPACT FACTOR: 7.02

*13. Prokop JW, Schmidt C, Gasper D, Duff RJ, Milsted A, Ohkubo T, Ball HC, Shawkey MD, Mays Jr HL, Cogburn LA, Londraville RL. Discovery of the elusive leptin in birds: Identification of several ‘missing links’ in the evolution of leptin and its receptor. PLOS One, 9:e92751 (2014). PMID: 24663438. IMPACT FACTOR: 2.81
12. Bilinovich SM, Davis CM, Morris DL, Ray LA, Prokop JW, Buchan GJ, Leeper TC. The C-terminal domain of SRA1p has a fold more similar to PRP18 than to an RRM and does not directly bind to the SRA1 RNA STR7 region. Journal of Molecular Biology, 426:1753-1765 (2014). PMID: 24486611. IMPACT FACTOR: 4.63
11. Peng H, Farrooji MTZ, Hou Z, Prokop JW, Osborne MJ, He M, Kebebew E, Orntoft T, Herlyn M, Caton AJ, Fredericks W, Malkowicz B, Speicher D, Skordalakes E, Borden KLB, Rauscher FJ III. LIMD2 is a small LIM-only protein which regulates cell motility and is a novel effector of tumor progression: Structural analysis suggests a role in the integrin-linked-kinase (ILK) pathway. Cancer Research, 74:1390 (2014). PMID: 24590809. IMPACT FACTOR: 9.33
10. Dores RM, Londraville R, Prokop J, Davis P, Dewey N, Lisinski N. MOLECULAR EVOLUTION OF GPCRS: Melanocortin/melanocortin receptors. Journal of Molecular Endocrinology, 52:T29-T42 (2014). PMID: 24868105. IMPACT FACTOR: 3.58
*9. Prokop JW, Rauscher FJ III, Peng H, Liu Y, Araujo FC, Watanabe I, Reis FM, Milsted A. MAS promoter regulation: A role of Sry and tyrosine nitration of the KRAB domain of ZNF274 as a feedback mechanism. Clinical Science, 126(10):727-738 (2014). PMID: 24128372. IMPACT FACTOR: 5.24

*8. Prokop JW, Milsted A, Liu Y, Peng H, Rauscher FJ III. A method for in silico localization of DNA binding sites for transcription factors using molecular dynamics and evolutionarily conserved amino acids: Application to the SNAIL/SLUG E-box binding zinc finger family. Journal of Molecular Modeling, 19(9):3463-3469 (2013). PMID: 23708613. IMPACT FACTOR: 1.34
*7. Prokop JW, Santos RAS, Milsted A. Differential mechanisms of activation of the Ang peptide receptors AT1, AT2, and MAS: Using in silico techniques to differentiate the three receptors. PLoS One, 8(6):e65307 (2013). PMID: 23755216. IMPACT FACTOR: 2.81
*6. Prokop JW, Underwood AC, Turner ME, Miller N, Pietrzak D, Scott S, Smith C, Milsted A. Analysis of Sry duplications on the Rattus norvegicus Y-chromosome. BMC Genomics, 14:792 (2013). PMID: 24228692. IMPACT FACTOR: 3.73

*5. Prokop JW, Watanabe IKM, Turner ME, Underwood AC, Martins AS, Milsted A. From rat to human, regulation of renin-angiotensin system genes by Sry. International Journal of Hypertension, 2012: 724240 (2012). PMID: 22315667. IMPACT FACTOR: 1.87
*4. Prokop JW, Duff RJ, Ball HC, Copeland DL, Londraville RL. Leptin and leptin receptor: analysis of a structure to function relationship in interaction and evolution from humans to fish. Peptides, 38(2):326-36 (2012). PMID: 23085324. IMPACT FACTOR: 2.66
*3. Prokop JW, Leeper T, Duan ZH, Milsted A. Amino acid function and docking site prediction through combining disease variants, structure alignments, sequence alignments, and molecular dynamics: A study of the HMG domain. BMC Bioinformatics, 13 (Suppl 2):S3 (2012). PMID: 22536866. IMPACT FACTOR: 2.45

2. Copeland DL, Duff RJ, Liu Q, Prokop J, Londraville RL. Leptin in Teleost Fishes: An Argument for Comparative Study. Frontiers in Physiology. 2:26 (2011). PMID: 21716655. IMPACT FACTOR: 3.2
1. Turner ME, Ely D, Prokop J, Milsted A. Sry, more than testis determination? American Journal of Physiology- Regulatory, Integrative and Comparative Physiology, 301(3):R561-571 (2011). PMID: 21677270. IMPACT FACTOR: 3.18