Helicase Google Drive Data

Helicase (Hel) (nsp13)– it has a zinc-binding domain in its N-terminus and it displays RNA and DNA duplex-unwinding activities with 5′ to 3′ polarity.² It also possesses the nucleoside triphosphate hydrolase (NTPase) that can hydrolyze all types of NTPs. Its helicase-activity is dependent on magnesium and NTPs.^2,23 Nsp13 is predicted to contain 596 amino acids. It has a triangular pyramid shape comprising five domains. Domains 1A (261-441 a.a), 2A (442-596 a.a), and 1B (150-260 a.a) form the triangular base. N-terminal zinc binding domain (ZBD) (1-99 a.a) and stalk domain (100-149 a.a) are arranged at the apex of the pyramid. NTPase active site residues include Lys288, Ser289, Asp374, Glu375, Gln404 and Arg567.²⁴ Bismuth salts could effectively inhibit both the NTPase and RNA helicase activities of nsp13 in a dose-dependent manner.²³

Helicase 5,598 Sequences

Amino Acid	AA	AA	Conservation	Conservation Z-score	RMSD_CA	RMSF[A]	Secondary Structure	DCCM >0.9
5325	A	ALA	19.20328689	-0.761347999	3.731	2.337	C	0
5326	V	VAL	19.04251518	-0.770600376	3.019	2.075	C	0
5327	G	GLY	45.21257592	0.735481028	2.439	1.249	E	1
5328	A	ALA	10.05716327	-1.287705459	2.386	1.272	E	2
5329	C	CYS	45.14112183	0.73136886	1.897	0.942	C	1
5330	V	VAL	44.49803501	0.694359351	1.634	1.442	C	0
5331	L	LEU	4.448017149	-1.61051062	3.263	1.742	C	0
5332	C	CYS	45.17684887	0.733424944	3.857	1.26	C	1
5333	N	ASN	13.82636656	-1.070788615	3.758	2.052	C	2
5334	S	SER	45.51625581	0.75295774	3.701	1.361	E	2
5335	Q	GLN	43.03322615	0.610059914	3.497	1.96	E	2
5336	T	THR	45.28403001	0.739593195	2.878	1.138	E	1
5337	S	SER	18.91747053	-0.77779667	2.713	1.318	C	0
5338	L	LEU	45.7484816	0.766322285	1.793	1.078	C	0
5339	R	ARG	45.87352626	0.773518578	1.941	1.357	E	0
5340	C	CYS	45.14112183	0.73136886	1.477	0.729	E	0
5341	G	GLY	46.32011433	0.799219626	1.684	0.991	C	0
5342	A	ALA	4.573061808	-1.603314326	1.346	1.061	C	0
5343	C	CYS	45.15898535	0.732396902	1.124	0.79	T	0
5344	I	ILE	29.72490175	-0.155831312	1	1.164	T	0
5345	R	ARG	45.28403001	0.739593195	0.873	0.885	T	0
5346	R	ARG	30.26080743	-0.124990054	1.047	1.512	T	0
5347	P	PRO	47.03465523	0.840341303	1.386	0.809	C	0
5348	F	PHE	20.22150768	-0.70274961	1.915	1.035	C	0
5349	L	LEU	46.80242944	0.826976758	1.972	1.002	C	1
5350	C	CYS	45.17684887	0.733424944	2.042	0.826	H	1
5351	C	CYS	28.42086459	-0.230878371	2.527	1.03	H	0
5352	K	LYS	43.60485888	0.642957255	2.291	1.72	H	1
5353	C	CYS	45.21257592	0.735481028	2.211	0.744	H	1
5354	C	CYS	25.72347267	-0.3861127	2.035	0.736	H	0
5355	Y	TYR	45.06966774	0.727256692	2.092	1.036	H	0
5356	D	ASP	43.35476956	0.628564669	2.251	0.993	H	0
5357	H	HIS	45.1947124	0.734452986	1.785	0.74	H	0
5358	V	VAL	46.9274741	0.834173051	1.546	1.014	H	1
5359	I	ILE	22.38299393	-0.578356538	2.017	1.269	H	1
5360	S	SER	6.627366917	-1.485089506	2.403	1.067	C	1
5361	T	THR	46.48088603	0.808472003	1.926	1.083	C	2
5362	S	SER	7.359771347	-1.442939788	1.741	1.18	C	2
5363	H	HIS	47.17756342	0.848565638	1.355	0.891	C	1
5364	K	LYS	44.67667024	0.70463977	1.376	1.249	C	0
5365	L	LEU	7.056091461	-1.4604165	1.464	1.131	E	0
5366	V	VAL	30.45730618	-0.113681593	1.611	0.992	E	0
5367	L	LEU	48.23151125	0.909220111	1.71	1.199	E	0
5368	S	SER	29.27831368	-0.18153236	2.256	1.419	C	0
5369	V	VAL	19.34619507	-0.753123664	2.858	2.137	C	0
5370	N	ASN	13.32618792	-1.099573789	2.537	1.801	C	1
5371	P	PRO	83.36906038	2.931378555	2.272	1.455	C	2
5372	Y	TYR	45.03394069	0.725200608	1.941	1.411	C	2
5373	V	VAL	35.38763844	0.170057975	2.414	1.529	C	3
5374	C	CYS	45.06966774	0.727256692	2.781	1.603	C	6
5375	N	ASN	21.77563416	-0.613309963	3.57	1.975	C	5
5376	A	ALA	29.74276527	-0.15480327	4.064	2.124	T	5
5377	P	PRO	25.93783494	-0.373776197	6.258	2.505	T	5
5378	G	GLY	31.79707038	-0.03657845	5.882	2.439	T	2
5379	C	CYS	45.21257592	0.735481028	3.946	2.049	T	6
5380	D	ASP	11.68274384	-1.194153645	3.172	2.197	C	1
5381	V	VAL	37.88853162	0.313983843	2.299	1.978	C	1
5382	T	THR	4.501607717	-1.607426494	2.251	1.874	C	0
5383	D	ASP	42.80100036	0.596695369	1.967	1.916	T	0
5384	V	VAL	53.26902465	1.199127931	1.621	1.517	T	0
5385	T	THR	43.28331547	0.624452501	1.673	1.741	T	0
5386	Q	GLN	7.734905323	-1.421350908	3.192	1.939	T	0
5387	L	LEU	79.528403	2.710349544	2.168	1.684	C	2
5388	Y	TYR	41.30046445	0.510339848	2.293	1.673	E	5
5389	L	LEU	44.48017149	0.693331309	2.849	2.131	E	3
5390	G	GLY	43.01536263	0.609031872	3.266	2.106	C	1
5391	G	GLY	45.37334762	0.744733405	4.699	2.59	C	1
5392	M	MET	26.54519471	-0.338822772	5.168	3.274	C	2
5393	S	SER	39.46052161	0.404451531	3.445	2.088	E	2
5394	Y	TYR	42.74740979	0.593611243	2.242	1.54	E	3
5395	Y	TYR	18.84601643	-0.781908837	2.032	1.815	E	6
5396	C	CYS	44.98035013	0.722116483	2.479	1.709	T	5
5397	K	LYS	4.876741693	-1.585837614	2.959	2.585	T	3
5398	S	SER	3.697749196	-1.65368838	3.233	2.261	T	3
5399	H	HIS	53.87638442	1.234081356	2.622	2.109	T	5
5400	K	LYS	41.37191854	0.514452016	2.329	2.188	C	4
5401	P	PRO	45.03394069	0.725200608	2.806	2.33	C	4
5402	P	PRO	4.448017149	-1.61051062	4.834	2.79	C	3
5403	I	ILE	17.84565916	-0.839479184	4.752	2.937	C	3
5404	S	SER	32.47588424	0.002487143	3.782	2.061	C	6
5405	F	PHE	35.53054662	0.17828231	4.156	2.727	C	2
5406	P	PRO	38.21007503	0.332488597	3.528	1.661	C	3
5407	L	LEU	42.92604502	0.603891663	2.504	1.548	E	1
5408	C	CYS	28.51018221	-0.225738162	3.372	1.38	E	0
5409	A	ALA	17.18470882	-0.877516735	4.048	1.567	E	0
5410	N	ASN	37.19185423	0.273890208	3.213	1.935	T	0
5411	G	GLY	45.06966774	0.727256692	2.529	1.154	T	0
5412	Q	GLN	4.358699536	-1.615650829	2.204	1.625	E	0
5413	V	VAL	66.29153269	1.948570486	2.505	1.388	E	0
5414	F	PHE	44.94462308	0.720060399	2.61	1.487	C	0
5415	G	GLY	45.40907467	0.746789489	2.808	1.344	T	1
5416	L	LEU	56.82386567	1.403708272	3.716	2.231	T	1
5417	Y	TYR	45.12325831	0.730340818	4.082	1.774	T	0
5418	K	LYS	37.44194355	0.288282795	4.464	2.611	T	1
5419	N	ASN	25.58056449	-0.394337036	4.414	2.637	C	1
5420	T	THR	7.949267596	-1.409014405	3.337	2.032	C	0
5421	C	CYS	26.81314755	-0.323402144	3.057	1.68	C	0
5422	V	VAL	9.199714184	-1.337051471	2.894	2.058	C	0
5423	G	GLY	45.3554841	0.743705363	2.551	1.194	C	0
5424	S	SER	46.83815648	0.829032842	2.67	1.193	C	0
5425	D	ASP	6.859592712	-1.471724961	3.67	1.606	C	0
5426	N	ASN	10.82529475	-1.243499657	2.584	1.317	H	0
5427	V	VAL	28.42086459	-0.230878371	2.498	1.496	H	0
5428	T	THR	4.465880672	-1.609482578	2.233	1.47	H	0
5429	D	ASP	31.90425152	-0.030410198	2.289	1.031	H	1
5430	F	PHE	45.14112183	0.73136886	2.238	0.839	H	1
5431	N	ASN	45.01607717	0.724172566	2.186	0.907	H	0
5432	A	ALA	3.804930332	-1.647520129	2.7	0.993	H	0
5433	I	ILE	20.20364416	-0.703777652	1.996	0.948	H	0
5434	A	ALA	43.60485888	0.642957255	1.925	0.92	H	0
5435	T	THR	35.65559128	0.185478604	2.633	1.024	C	0
5436	C	CYS	18.81028939	-0.783964921	2.492	1.038	C	0
5437	D	ASP	28.76027153	-0.211345575	3.696	1.114	C	0
5438	W	TRP	42.89031797	0.601835579	1.658	0.895	C	0
5439	T	THR	32.27938549	-0.008821318	1.817	1.211	E	1
5440	N	ASN	6.555912826	-1.489201674	1.873	1.291	E	3
5441	A	ALA	4.108610218	-1.630043416	2.04	1.096	E	1
5442	G	GLY	11.66488031	-1.195181687	2.085	0.983	H	0
5443	D	ASP	35.3519114	0.168001891	2.384	1.041	H	0
5444	Y	TYR	44.98035013	0.722116483	1.923	0.884	H	1
5445	I	ILE	16.41657735	-0.921722538	1.9	1.189	H	2
5446	L	LEU	42.90818149	0.602863621	1.788	1.172	H	1
5447	A	ALA	45.99857092	0.780714872	1.457	0.923	H	0
5448	N	ASN	45.1947124	0.734452986	1.246	0.919	C	0
5449	T	THR	13.23687031	-1.104713998	1.278	1.069	C	0
5450	C	CYS	18.97106109	-0.774712544	1.337	0.888	C	1
5451	T	THR	18.57806359	-0.797329466	1.485	1.203	H	1
5452	E	GLU	23.25830654	-0.527982485	1.598	1.144	H	0
5453	R	ARG	11.16470168	-1.22396686	1.319	1.836	H	0
5454	L	LEU	45.05180422	0.72622865	1.382	0.949	H	0
5455	K	LYS	37.49553412	0.291366921	1.384	1.094	H	0
5456	L	LEU	37.13826367	0.270806083	1.002	0.886	H	1
5457	F	PHE	44.76598785	0.70977998	1.067	0.774	H	1
5458	A	ALA	47.40978921	0.861930183	1.205	0.822	H	0
5459	A	ALA	46.67738478	0.819780464	1.164	0.848	H	1
5460	E	GLU	45.64130046	0.760154033	0.899	0.828	H	2
5461	T	THR	45.10539478	0.729312776	1.038	0.805	H	2
5462	L	LEU	12.93319043	-1.122190711	1.306	1.149	H	2
5463	K	LYS	36.6916756	0.245105035	1.195	1.082	H	2
5464	A	ALA	45.01607717	0.724172566	0.864	0.903	H	2
5465	T	THR	26.27724187	-0.354243401	1.04	0.894	H	2
5466	E	GLU	45.05180422	0.72622865	1.107	1.132	H	2
5467	E	GLU	45.08753126	0.728284734	1.032	0.872	H	2
5468	T	THR	3.769203287	-1.649576213	1.133	0.979	H	2
5469	F	PHE	10.25366202	-1.276396998	1.322	1.108	H	2
5470	K	LYS	44.9624866	0.721088441	1.264	1.054	H	3
5471	L	LEU	3.876384423	-1.643407961	1.314	1.322	C	2
5472	S	SER	36.49517685	0.233796574	1.399	1.248	C	3
5473	Y	TYR	38.26366559	0.335572723	1.533	1.352	C	3
5474	G	GLY	7.734905323	-1.421350908	1.719	1.402	C	2
5475	I	ILE	11.82565202	-1.185929309	1.683	1.707	E	7
5476	A	ALA	50.30367989	1.028472973	1.518	1.604	E	10
5477	T	THR	36.08431583	0.21015161	1.652	1.792	E	14
5478	V	VAL	13.95141122	-1.063592322	1.811	1.785	E	15
5479	R	ARG	14.34440872	-1.0409754	1.898	2.867	E	11
5480	E	GLU	48.71382637	0.936977243	1.899	2.373	E	11
5481	V	VAL	29.40335834	-0.174336066	2.067	1.936	C	8
5482	L	LEU	9.914255091	-1.295929794	1.969	2.177	C	5
5483	S	SER	20.471597	-0.688357023	1.756	1.761	C	3
5484	D	ASP	15.46981065	-0.976208759	1.863	2.006	C	1
5485	R	ARG	29.09967846	-0.191812779	1.408	2.682	E	0
5486	E	GLU	37.01321901	0.263609789	1.386	1.722	E	1
5487	L	LEU	42.47945695	0.578190615	1.328	1.839	E	5
5488	H	HIS	3.751339764	-1.650604254	1.605	2.123	E	8
5489	L	LEU	49.53554841	0.984267171	1.657	1.709	E	8
5490	S	SER	22.41872097	-0.576300454	1.673	1.958	E	9
5491	W	TRP	45.5877099	0.757069908	1.939	1.782	E	9
5492	E	GLU	45.17684887	0.733424944	1.896	1.841	C	6
5493	V	VAL	20.90032154	-0.663684017	2.128	2.307	C	2
5494	G	GLY	47.83851375	0.886603189	2.223	2.218	C	1
5495	K	LYS	35.9056806	0.19987119	2.046	2.158	C	1
5496	P	PRO	15.29117542	-0.986489178	1.975	1.634	C	2
5497	R	ARG	14.82672383	-1.013218268	2.11	1.928	C	2
5498	P	PRO	45.9807074	0.77968683	2.431	1.368	C	1
5499	P	PRO	45.03394069	0.725200608	2.42	1.458	C	0
5500	L	LEU	43.96212933	0.663518094	1.696	1.77	C	0
5501	N	ASN	42.6759557	0.589499076	2.482	1.653	T	0
5502	R	ARG	36.2986781	0.222488113	1.646	1.668	T	0
5503	N	ASN	45.80207217	0.769406411	1.415	1.726	T	0
5504	Y	TYR	26.20578778	-0.358355569	1.826	1.235	T	0
5505	V	VAL	42.81886388	0.597723411	1.247	1.411	E	0
5506	F	PHE	47.15969989	0.847537596	0.98	1.157	E	1
5507	T	THR	44.78385138	0.710808022	1.287	1.289	E	4
5508	G	GLY	28.40300107	-0.231906413	1.313	1.254	E	7
5509	Y	TYR	38.31725616	0.338656849	1.669	1.588	E	9
5510	R	ARG	3.697749196	-1.65368838	2.12	2.162	E	6
5511	V	VAL	4.78742408	-1.590977823	2.247	2.102	E	4
5512	T	THR	38.63879957	0.357161603	2.455	2.562	E	2
5513	K	LYS	36.03072526	0.207067484	2.818	4.041	T	1
5514	N	ASN	31.11825652	-0.075644042	4.057	3.709	T	1
5515	S	SER	24.99106824	-0.428262419	3.411	2.635	E	2
5516	K	LYS	44.64094319	0.702583686	2.369	2.793	E	4
5517	V	VAL	19.73919257	-0.730506742	2.276	2.168	E	4
5518	Q	GLN	38.37084673	0.341740975	1.991	1.944	E	5
5519	I	ILE	15.0410861	-1.000881765	1.767	1.566	E	3
5520	G	GLY	45.08753126	0.728284734	1.562	1.223	E	1
5521	E	GLU	37.04894605	0.265665873	1.201	1.236	E	0
5522	Y	TYR	21.34690961	-0.637982969	1.041	1.166	E	1
5523	T	THR	12.23651304	-1.162284345	1.04	1.233	E	2
5524	F	PHE	43.03322615	0.610059914	1.287	1.503	E	2
5525	E	GLU	38.06716685	0.324264262	1.831	1.928	E	2
5526	K	LYS	35.31618435	0.165945807	2.452	3.222	E	2
5527	G	GLY	11.64701679	-1.196209729	1.728	1.814	C	2
5528	D	ASP	18.20292962	-0.818918346	2.348	2.24	C	1
5529	Y	TYR	28.63522687	-0.218541868	2.251	3.234	T	0
5530	G	GLY	28.72454448	-0.213401659	4.11	2.528	T	1
5531	D	ASP	38.67452662	0.359217687	2.74	2.105	T	2
5532	A	ALA	48.51732762	0.925668782	1.746	1.798	E	2
5533	V	VAL	42.80100036	0.596695369	1.367	1.576	E	2
5534	V	VAL	4.769560557	-1.592005865	1.389	1.682	E	2
5535	Y	TYR	44.15862808	0.674826555	1.326	1.22	E	2
5536	R	ARG	21.40050018	-0.634898844	1.19	1.507	E	1
5537	G	GLY	7.288317256	-1.447051955	1.279	1.087	T	0
5538	T	THR	39.83565559	0.426040411	1.786	1.184	T	0
5539	T	THR	23.47266881	-0.515645982	1.839	1.716	T	0
5540	T	THR	45.55198285	0.755013824	2.107	1.998	T	0
5541	Y	TYR	21.93640586	-0.604057586	1.92	1.866	C	1
5542	K	LYS	47.53483387	0.869126476	1.838	2.513	C	2
5543	L	LEU	46.28438728	0.797163542	1.637	1.592	C	4
5544	N	ASN	3.644158628	-1.656772506	2.06	1.964	T	5
5545	V	VAL	27.0096463	-0.312093683	2.1	2.043	T	10
5546	G	GLY	50.96463023	1.066510524	2.047	1.815	T	8
5547	D	ASP	69.79278314	2.150066701	1.821	1.614	E	11
5548	Y	TYR	10.84315827	-1.242471615	1.575	2.09	E	11
5549	F	PHE	43.01536263	0.609031872	1.323	1.413	E	8
5550	V	VAL	61.14683816	1.652494415	1.267	1.673	E	4
5551	L	LEU	51.9649875	1.124080871	1.593	1.489	E	0
5552	T	THR	42.65809218	0.588471034	2.76	1.618	C	0
5553	S	SER	42.92604502	0.603891663	1.959	1.325	C	0
5554	H	HIS	44.9624866	0.721088441	1.941	1.34	C	0
5555	T	THR	3.929974991	-1.640323835	2.246	1.345	C	0
5556	V	VAL	45.01607717	0.724172566	0.832	1.05	C	0
5557	M	MET	3.679885673	-1.654716422	0.828	1.562	C	0
5558	P	PRO	22.3651304	-0.57938458	0.807	0.947	C	0
5559	L	LEU	45.51625581	0.75295774	0.917	0.916	C	0
5560	S	SER	14.43372633	-1.03583519	1.486	1.125	C	0
5561	A	ALA	80.90389425	2.789508771	1.254	0.948	C	0
5562	P	PRO	43.83708467	0.6563218	0.875	0.937	C	0
5563	T	THR	40.92533048	0.488750968	1.217	0.921	C	0
5564	L	LEU	24.45516256	-0.459103676	1.531	1.204	C	0
5565	V	VAL	20.73954984	-0.672936394	1.75	1.088	C	0
5566	P	PRO	18.5066095	-0.801441634	1.679	1.204	C	0
5567	Q	GLN	45.96284387	0.778658788	1.574	1.757	C	0
5568	E	GLU	37.12040014	0.269778041	1.84	1.368	C	0
5569	H	HIS	3.965702036	-1.638267751	1.965	1.38	C	0
5570	Y	TYR	37.42408003	0.287254753	2.239	1.195	C	1
5571	V	VAL	14.34440872	-1.0409754	2.636	1.778	C	2
5572	R	ARG	13.36191497	-1.097517705	1.773	2.021	C	2
5573	I	ILE	34.40514469	0.11351567	1.406	1.157	C	2
5574	T	THR	14.30868167	-1.043031483	1.397	1.129	C	1
5575	G	GLY	15.73776349	-0.96078813	1.411	1.07	C	0
5576	L	LEU	37.95998571	0.318096011	1.409	1	C	1
5577	Y	TYR	15.00535906	-1.002937849	1.436	1.407	C	1
5578	P	PRO	38.1922115	0.331460555	1.556	1.016	C	0
5579	T	THR	13.11182565	-1.111910292	1.576	1.217	C	0
5580	L	LEU	5.305466238	-1.561164608	2.103	2.128	C	0
5581	N	ASN	20.90032154	-0.663684017	3.339	2.07	C	0
5582	I	ILE	17.43479814	-0.863124148	2.22	1.395	C	0
5583	S	SER	6.573776349	-1.488173632	1.875	1.266	T	0
5584	D	ASP	7.109682029	-1.457332375	1.655	1.477	T	0
5585	E	GLU	11.59342622	-1.199293854	1.479	1.645	T	0
5586	F	PHE	26.04501608	-0.367607946	1.279	0.969	T	0
5587	S	SER	15.6663094	-0.964900298	1.052	1.116	C	0
5588	S	SER	21.82922472	-0.610225838	1.134	1.164	C	0
5589	N	ASN	18.27438371	-0.814806178	0.949	1.147	H	0
5590	V	VAL	48.35655591	0.916416404	1.215	1.258	H	0
5591	A	ALA	12.14719543	-1.167424555	1.24	1.051	H	0
5592	N	ASN	18.07788496	-0.82611464	1.064	0.973	H	0
5593	Y	TYR	37.04894605	0.265665873	1.197	0.803	H	1
5594	Q	GLN	35.10182208	0.153609304	1.207	0.931	H	2
5595	K	LYS	11.61128975	-1.198265812	1.075	1.283	H	1
5596	V	VAL	13.07609861	-1.113966375	1.05	0.915	H	0
5597	G	GLY	44.35512683	0.686135016	1.055	0.759	H	0
5598	M	MET	13.09396213	-1.112938333	1.219	1.242	H	0
5599	Q	GLN	30.85030368	-0.091064671	1.072	0.953	C	0
5600	K	LYS	34.15505538	0.099123083	1.147	1.192	E	0
5601	Y	TYR	19.09610575	-0.76751625	0.898	1.071	E	0
5602	S	SER	20.73954984	-0.672936394	0.684	0.717	E	0
5603	T	THR	46.17720615	0.790995291	0.899	0.853	E	0
5604	L	LEU	8.288674527	-1.389481608	1.032	1.017	E	0
5605	Q	GLN	45.48052876	0.750901656	0.938	0.725	E	0
5606	G	GLY	48.53519114	0.926696824	1.123	0.679	E	0
5607	P	PRO	75.06252233	2.453339066	1.136	0.698	T	0
5608	P	PRO	47.46337978	0.865014309	1.243	0.821	T	0
5609	G	GLY	53.01893533	1.184735344	0.854	0.808	T	0
5610	T	THR	24.3301179	-0.46629997	1.191	0.889	T	0
5611	G	GLY	56.66309396	1.394455894	1.468	0.948	C	0
5612	K	LYS	47.7134691	0.879406895	1.442	1.063	C	0
5613	S	SER	45.39121115	0.745761447	1.208	0.864	C	0
5614	H	HIS	44.99821365	0.723144525	1.325	1.201	H	0
5615	F	PHE	21.52554484	-0.62770255	1.056	0.972	H	0
5616	A	ALA	29.38549482	-0.175364108	0.904	0.916	H	0
5617	I	ILE	45.71275456	0.764266201	1.039	0.99	H	0
5618	G	GLY	44.83744194	0.713892147	1.106	0.744	H	0
5619	L	LEU	70.68595927	2.201468797	1.058	1.085	H	0
5620	A	ALA	29.77849232	-0.152747186	0.792	0.837	H	0
5621	L	LEU	21.16827438	-0.648263388	0.811	1.21	H	0
5622	Y	TYR	42.94390854	0.604919704	0.845	0.79	H	0
5623	Y	TYR	35.67345481	0.186506646	0.889	0.712	H	0
5624	P	PRO	30.92175777	-0.086952504	1.067	0.914	C	0
5625	S	SER	7.877813505	-1.413126572	0.968	0.992	C	0
5626	A	ALA	45.46266524	0.749873614	0.923	0.87	C	0
5627	R	ARG	45.56984637	0.756041866	0.791	1.086	E	0
5628	I	ILE	24.74097892	-0.442655006	0.626	0.842	E	0
5629	V	VAL	42.97963558	0.606975788	0.717	0.88	E	0
5630	Y	TYR	22.9903537	-0.543403113	0.624	0.639	E	0
5631	T	THR	42.42586638	0.575106489	0.796	0.821	E	0
5632	A	ALA	44.69453376	0.705667812	0.69	0.808	E	0
5633	C	CYS	35.97713469	0.203983358	0.746	0.867	C	0
5634	S	SER	43.58699536	0.641929213	0.8	0.852	H	0
5635	H	HIS	44.76598785	0.70977998	0.702	0.897	H	0
5636	A	ALA	44.67667024	0.70463977	0.832	0.96	H	0
5637	A	ALA	44.74812433	0.708751938	0.787	0.897	H	0
5638	V	VAL	43.05108967	0.611087956	0.593	0.884	H	0
5639	D	ASP	49.66059307	0.991463464	0.68	0.762	H	0
5640	A	ALA	33.47624151	0.06005749	0.756	0.914	H	0
5641	L	LEU	58.44944623	1.497260086	0.623	0.894	H	0
5642	C	CYS	44.83744194	0.713892147	0.647	0.701	H	1
5643	E	GLU	32.65451947	0.012767562	0.791	1.173	H	1
5644	K	LYS	45.99857092	0.780714872	0.97	1.36	H	0
5645	A	ALA	45.55198285	0.755013824	0.854	0.884	H	0
5646	L	LEU	4.126473741	-1.629015374	0.996	1.194	H	0
5647	K	LYS	31.60057163	-0.047886911	1.408	1.704	H	0
5648	Y	TYR	11.86137906	-1.183873226	1.29	1.045	C	0
5649	L	LEU	53.0725259	1.18781947	1.173	0.996	C	0
5650	P	PRO	8.092175777	-1.400790069	1.462	1.158	T	0
5651	I	ILE	20.45373348	-0.689385065	1.651	1.73	T	0
5652	D	ASP	28.01000357	-0.254523335	1.128	1.442	T	0
5653	K	LYS	27.22400857	-0.29975718	1.126	1.464	E	0
5654	C	CYS	46.28438728	0.797163542	0.901	0.862	E	1
5655	S	SER	29.18899607	-0.186672569	0.832	0.842	E	1
5656	R	ARG	74.13361915	2.399880886	0.853	1.074	E	1
5657	I	ILE	46.21293319	0.793051375	0.913	1.083	E	1
5658	I	ILE	32.94033583	0.029216233	1.191	1.338	C	0
5659	P	PRO	73.07967131	2.339226413	1.524	1.279	C	0
5660	A	ALA	37.8706681	0.312955801	1.373	1.501	C	0
5661	R	ARG	29.18899607	-0.186672569	1.596	1.895	C	0
5662	A	ALA	32.88674527	0.026132107	1.685	1.186	C	0
5663	R	ARG	37.79921401	0.308843633	1.411	1.414	C	0
5664	V	VAL	42.6759557	0.589499076	0.844	1.1	C	0
5665	E	GLU	35.06609503	0.151553221	1.479	1.386	C	0
5666	C	CYS	44.78385138	0.710808022	1.257	1.327	C	0
5667	F	PHE	14.77313326	-1.016302394	0.94	1.119	C	0
5668	D	ASP	29.68917471	-0.157887396	1.421	1.361	C	0
5669	K	LYS	18.43515541	-0.805553801	0.968	1.606	C	0
5670	F	PHE	44.67667024	0.70463977	0.911	0.985	C	1
5671	K	LYS	43.74776706	0.651181591	0.973	1.374	E	2
5672	V	VAL	15.75562701	-0.959760088	1.159	1.551	E	1
5673	N	ASN	46.23079671	0.794079417	1.065	1.088	E	0
5674	S	SER	4.412290104	-1.612566704	1.226	1.029	C	0
5675	T	THR	44.10503751	0.671742429	1.72	1.088	C	0
5676	L	LEU	4.019292605	-1.635183626	1.365	1.623	C	1
5677	E	GLU	6.287959986	-1.504622303	1.119	0.963	C	2
5678	Q	GLN	32.08288675	-0.020129779	0.843	0.966	E	2
5679	Y	TYR	45.96284387	0.778658788	0.713	0.778	E	1
5680	V	VAL	16.66666667	-0.907329951	0.687	0.93	E	0
5681	F	PHE	44.62307967	0.701555644	0.621	0.69	E	0
5682	C	CYS	6.698821008	-1.480977339	0.717	0.826	E	0
5683	T	THR	46.35584137	0.80127571	0.765	0.912	T	0
5684	V	VAL	21.36477313	-0.636954927	0.878	1.005	T	0
5685	N	ASN	44.8017149	0.711836064	1.094	1.282	T	0
5686	A	ALA	45.62343694	0.759125992	1.044	1.088	T	0
5687	L	LEU	45.10539478	0.729312776	1.117	1.181	C	0
5688	P	PRO	47.03465523	0.840341303	1.18	1.067	C	0
5689	E	GLU	42.97963558	0.606975788	1.464	1.415	C	0
5690	T	THR	12.37942122	-1.15406001	1.82	1.299	C	0
5691	T	THR	4.644515899	-1.599202159	2.07	1.128	C	0
5692	A	ALA	28.83172562	-0.207233407	1.004	0.919	C	0
5693	D	ASP	46.71311183	0.821836548	0.764	0.776	E	0
5694	I	ILE	45.65916399	0.761182075	0.781	0.869	E	0
5695	V	VAL	31.45766345	-0.056111246	0.833	0.901	E	0
5696	V	VAL	44.53376206	0.696415435	0.774	0.873	E	0
5697	F	PHE	5.448374419	-1.552940273	0.876	0.811	E	0
5698	D	ASP	47.37406217	0.859874099	0.841	0.637	E	0
5699	E	GLU	46.6952483	0.820808506	0.846	0.786	T	0
5700	I	ILE	5.894962487	-1.527239225	0.949	1.084	T	0
5701	S	SER	44.99821365	0.723144525	0.92	0.755	T	0
5702	M	MET	44.94462308	0.720060399	0.706	1.272	T	0
5703	A	ALA	6.234369418	-1.507706428	1	0.928	C	0
5704	T	THR	44.98035013	0.722116483	1.216	0.93	H	0
5705	N	ASN	45.15898535	0.732396902	0.995	0.791	H	1
5706	Y	TYR	44.74812433	0.708751938	0.73	0.807	H	2
5707	D	ASP	28.77813505	-0.210317533	0.926	0.725	H	2
5708	L	LEU	45.24830297	0.737537111	0.97	0.899	H	2
5709	S	SER	44.87316899	0.715948231	0.914	0.686	H	1
5710	V	VAL	26.42015005	-0.346019066	1.056	0.941	H	0
5711	V	VAL	7.038227939	-1.461444542	1.252	0.977	H	0
5712	N	ASN	44.76598785	0.70977998	1.323	0.985	H	0
5713	A	ALA	22.16863165	-0.590693041	1.268	0.972	H	0
5714	R	ARG	38.67452662	0.359217687	1.37	1.264	H	0
5715	L	LEU	11.21829225	-1.220882734	1.772	0.969	H	0
5716	R	ARG	11.14683816	-1.224994902	1.73	1.827	C	0
5717	A	ALA	18.72097178	-0.789105131	0.733	0.915	C	0
5718	K	LYS	24.45516256	-0.459103676	0.825	1.75	C	0
5719	H	HIS	63.7013219	1.799504408	0.864	0.74	E	0
5720	Y	TYR	10.66452304	-1.252752034	0.793	0.765	E	0
5721	V	VAL	45.33762058	0.742677321	0.768	0.866	E	0
5722	Y	TYR	44.58735263	0.699499561	0.881	0.675	E	0
5723	I	ILE	10.50375134	-1.262004411	0.906	0.854	E	0
5724	G	GLY	44.89103251	0.716976273	1.11	0.743	E	0
5725	D	ASP	45.96284387	0.778658788	0.885	0.677	T	0
5726	P	PRO	45.05180422	0.72622865	0.843	0.846	T	0
5727	A	ALA	26.0628796	-0.366579904	0.839	0.849	T	0
5728	Q	GLN	45.23043944	0.736509069	0.761	0.806	T	0
5729	L	LEU	45.01607717	0.724172566	1.128	1.535	C	0
5730	P	PRO	44.71239728	0.706695854	0.96	1.067	C	0
5731	A	ALA	45.08753126	0.728284734	0.951	1.136	C	0
5732	P	PRO	44.65880672	0.703611728	1.075	1.374	C	0
5733	R	ARG	44.89103251	0.716976273	2.166	1.658	C	0
5734	T	THR	25.97356199	-0.371720114	1.396	1.603	C	0
5735	L	LEU	32.26152197	-0.00984936	1.173	1.407	C	1
5736	L	LEU	28.84958914	-0.206205366	1.631	1.269	C	2
5737	T	THR	17.5598428	-0.855927855	1.707	1.456	C	1
5738	K	LYS	16.04144337	-0.943311418	1.64	2.003	E	1
5739	G	GLY	46.10575205	0.786883123	1.979	1.312	C	0
5740	T	THR	42.81886388	0.597723411	2.087	1.757	C	0
5741	L	LEU	47.67774205	0.877350812	1.198	1.497	C	0
5742	E	GLU	31.4933905	-0.054055162	0.793	1.266	T	0
5743	P	PRO	60.27152554	1.602120361	0.792	0.865	T	0
5744	E	GLU	39.38906752	0.400339364	1.186	1.287	T	0
5745	Y	TYR	10.64665952	-1.253780076	0.943	1.067	T	0
5746	F	PHE	18.57806359	-0.797329466	0.732	0.752	C	0
5747	N	ASN	45.48052876	0.750901656	0.798	0.845	H	0
5748	S	SER	13.73704895	-1.075928825	0.719	0.797	H	0
5749	V	VAL	58.46730975	1.498288128	0.632	1.146	H	0
5750	C	CYS	4.251518399	-1.621819081	0.66	0.969	H	0
5751	R	ARG	18.27438371	-0.814806178	0.789	1.484	H	0
5752	L	LEU	39.56770275	0.410619783	0.776	1.426	H	0
5753	M	MET	45.06966774	0.727256692	0.794	1.139	H	0
5754	K	LYS	5.680600214	-1.539575728	1.306	1.422	H	0
5755	T	THR	6.788138621	-1.475837129	1.268	1.478	H	0
5756	I	ILE	8.985351911	-1.349387974	1.312	1.62	H	0
5757	G	GLY	28.54590925	-0.223682078	0.898	0.849	C	0
5758	P	PRO	42.8367274	0.598751453	0.933	0.848	C	0
5759	D	ASP	46.01643444	0.781742914	0.953	0.819	C	0
5760	M	MET	4.573061808	-1.603314326	1.044	0.918	E	0
5761	F	PHE	44.74812433	0.708751938	1.179	0.887	E	0
5762	L	LEU	47.30260807	0.855761931	1.357	1.001	E	0
5763	G	GLY	10.7895677	-1.24555574	1.373	0.932	E	0
5764	T	THR	13.57627724	-1.085181202	1.266	1.118	E	0
5765	C	CYS	44.65880672	0.703611728	1.144	0.821	E	1
5766	R	ARG	3.929974991	-1.640323835	0.972	1.514	C	1
5767	R	ARG	46.60593069	0.815668297	2.497	2.299	C	1
5768	C	CYS	44.74812433	0.708751938	1.71	0.965	C	2
5769	P	PRO	47.96355841	0.893799482	1.388	1.168	H	1
5770	A	ALA	20.471597	-0.688357023	1.558	1.186	H	0
5771	E	GLU	45.17684887	0.733424944	1.248	1.022	H	0
5772	I	ILE	44.03358342	0.667630261	1.089	1.085	H	0
5773	V	VAL	45.65916399	0.761182075	1.392	1.005	H	0
5774	D	ASP	22.41872097	-0.576300454	2.099	1.211	H	0
5775	T	THR	45.40907467	0.746789489	1.681	0.953	H	0
5776	V	VAL	46.82029296	0.8280048	1.184	0.955	H	0
5777	S	SER	44.8017149	0.711836064	1.368	1.051	H	0
5778	A	ALA	24.24080029	-0.471440179	1.297	1.348	H	0
5779	L	LEU	34.70882458	0.130992382	1.25	1.401	C	0
5780	V	VAL	45.65916399	0.761182075	1.015	1.265	C	0
5781	Y	TYR	44.78385138	0.710808022	1.299	0.751	T	0
5782	D	ASP	18.41729189	-0.806581843	1.536	1.172	T	0
5783	N	ASN	38.22793855	0.333516639	1.896	1.357	T	0
5784	K	LYS	34.24437299	0.104263292	2.051	1.459	T	0
5785	L	LEU	23.09753483	-0.537234862	1.454	0.975	C	0
5786	K	LYS	14.70167917	-1.020414561	1.233	1.89	E	0
5787	A	ALA	28.20650232	-0.243214874	1.101	1.133	C	0
5788	H	HIS	3.733476242	-1.651632296	1.316	1.53	C	0
5789	K	LYS	17.68488746	-0.848731562	2.073	1.75	C	1
5790	D	ASP	5.180421579	-1.568360901	2.072	1.793	C	2
5791	K	LYS	4.269381922	-1.620791039	1.801	2.213	C	1
5792	S	SER	44.71239728	0.706695854	1.325	1.483	C	0
5793	A	ALA	27.20614505	-0.300785222	1.76	1.537	C	0
5794	Q	GLN	65.88067167	1.924925522	1.455	1.758	E	1
5795	C	CYS	44.83744194	0.713892147	1.287	1.093	E	2
5796	F	PHE	43.56913183	0.640901171	1.383	1.431	E	2
5797	K	LYS	46.49874955	0.809500045	1.385	1.254	E	2
5798	M	MET	6.341550554	-1.501538177	1.729	1.805	E	3
5799	F	PHE	18.63165416	-0.79424534	2.274	1.682	E	4
5800	Y	TYR	17.20257235	-0.876488693	2.499	1.913	E	6
5801	K	LYS	33.69060379	0.072393993	2.768	2.66	C	5
5802	G	GLY	35.15541265	0.15669343	2.682	2.062	C	6
5803	V	VAL	8.663808503	-1.367892728	2.806	2.763	C	1
5804	I	ILE	4.215791354	-1.623875165	2.597	2.525	C	0
5805	T	THR	18.56020007	-0.798357508	2.922	3.33	E	0
5806	H	HIS	28.06359414	-0.25143921	5.575	4.143	C	1
5807	D	ASP	26.56305824	-0.33779473	6.245	4.497	C	2
5808	V	VAL	3.965702036	-1.638267751	5.28	3.238	C	1
5809	S	SER	18.63165416	-0.79424534	4.553	3.178	C	0
5810	S	SER	44.73026081	0.707723896	2.419	2.287	C	0
5811	A	ALA	28.15291175	-0.246299	3.177	2.253	C	3
5812	I	ILE	27.68846016	-0.27302809	2.931	2.259	E	6
5813	N	ASN	44.67667024	0.70463977	2.81	2.04	H	5
5814	R	ARG	25.59842801	-0.393308994	2.84	2.581	H	7
5815	P	PRO	12.45087531	-1.149947842	2.451	1.934	H	6
5816	Q	GLN	44.64094319	0.702583686	2.211	1.816	H	7
5817	I	ILE	10.73597713	-1.248639866	2.735	1.772	H	6
5818	G	GLY	4.32297249	-1.617706913	2.527	1.603	H	7
5819	V	VAL	20.66809575	-0.677048562	2.063	1.705	H	5
5820	V	VAL	38.06716685	0.324264262	2.213	1.46	H	6
5821	R	ARG	16.09503394	-0.940227292	2.305	2.134	H	6
5822	E	GLU	4.644515899	-1.599202159	2.274	1.787	H	6
5823	F	PHE	44.92675956	0.719032357	2.039	1.43	H	7
5824	L	LEU	35.86995355	0.197815107	2.058	1.899	H	6
5825	T	THR	13.8620936	-1.068732531	2.211	1.783	H	5
5826	R	ARG	11.59342622	-1.199293854	2.197	2.303	H	4
5827	N	ASN	44.19435513	0.676882638	2.173	1.539	H	6
5828	P	PRO	34.70882458	0.130992382	2.385	1.814	T	3
5829	A	ALA	11.36120043	-1.212658399	3.028	1.76	T	2
5830	W	TRP	44.74812433	0.708751938	2.539	1.344	T	4
5831	R	ARG	13.41550554	-1.094433579	2.542	2.177	T	1
5832	K	LYS	33.3869239	0.054917281	2.446	3.446	C	0
5833	A	ALA	42.72954627	0.592583202	1.856	1.424	C	1
5834	V	VAL	34.99464094	0.147441053	1.741	1.596	E	2
5835	F	PHE	44.83744194	0.713892147	1.743	1.204	E	3
5836	I	ILE	44.98035013	0.722116483	1.617	1.329	E	2
5837	S	SER	45.21257592	0.735481028	1.806	1.258	C	7
5838	P	PRO	45.15898535	0.732396902	2.152	1.519	C	4
5839	Y	TYR	45.12325831	0.730340818	1.984	1.668	H	8
5840	N	ASN	45.65916399	0.761182075	2.032	1.953	H	8
5841	S	SER	35.61986424	0.18342252	2.224	1.827	H	8
5842	Q	GLN	36.37013219	0.22660028	2.174	1.67	H	10
5843	N	ASN	44.74812433	0.708751938	1.818	1.413	H	9
5844	A	ALA	11.84351554	-1.184901267	2.344	1.792	H	8
5845	V	VAL	29.93926402	-0.143494809	2.574	1.983	H	8
5846	A	ALA	44.62307967	0.701555644	2.08	1.614	H	8
5847	S	SER	17.63129689	-0.851815687	2.476	1.776	H	7
5848	K	LYS	25.61629153	-0.392280952	3.13	2.659	H	7
5849	I	ILE	4.841014648	-1.587893698	2.996	1.953	H	6
5850	L	LEU	43.8549482	0.657349842	2.399	1.696	H	6
5851	G	GLY	84.7266881	3.009509741	2.966	1.703	C	5
5852	L	LEU	42.56877456	0.583330824	2.189	1.61	C	3
5853	P	PRO	3.733476242	-1.651632296	1.919	1.47	E	2
5854	T	THR	25.09824937	-0.422094167	1.863	1.574	E	1
5855	Q	GLN	46.26652376	0.7961355	1.938	1.835	E	1
5856	T	THR	45.03394069	0.725200608	1.949	1.315	H	1
5857	V	VAL	64.57663451	1.849878462	2.635	1.587	H	0
5858	D	ASP	44.83744194	0.713892147	2.103	1.512	H	0
5859	S	SER	44.8017149	0.711836064	2.311	1.398	H	0
5860	S	SER	62.50446588	1.7306256	3.348	1.14	H	0
5861	Q	GLN	44.89103251	0.716976273	2.384	1.63	H	0
5862	G	GLY	44.99821365	0.723144525	2.413	1.207	C	0
5863	S	SER	44.87316899	0.715948231	1.788	1.318	C	0
5864	E	GLU	44.78385138	0.710808022	1.592	1.457	C	1
5865	Y	TYR	44.31939979	0.684078932	1.655	1.373	E	2
5866	D	ASP	36.90603787	0.257441538	1.666	1.285	C	2
5867	Y	TYR	44.30153626	0.68305089	1.788	1.579	E	2
5868	V	VAL	49.8392283	1.001743883	1.618	1.388	E	2
5869	I	ILE	45.1947124	0.734452986	1.865	1.245	E	2
5870	F	PHE	22.81171847	-0.553683532	1.943	1.264	E	1
5871	T	THR	17.91711325	-0.835367017	1.83	1.442	E	2
5872	Q	GLN	35.22686674	0.160805598	1.979	1.742	C	2
5873	T	THR	46.23079671	0.794079417	1.994	1.627	C	1
5874	T	THR	6.234369418	-1.507706428	2.533	1.921	C	0
5875	E	GLU	11.59342622	-1.199293854	2.246	1.861	C	2
5876	T	THR	35.33404787	0.166973849	2.564	2.205	T	2
5877	A	ALA	34.76241515	0.134076508	2.365	2.219	T	2
5878	H	HIS	44.78385138	0.710808022	1.824	3.024	T	0
5879	S	SER	10.7895677	-1.24555574	1.578	1.489	T	0
5880	C	CYS	16.47016792	-0.918638412	1.609	1.36	C	0
5881	N	ASN	54.34083601	1.260810446	2.09	1.126	H	0
5882	V	VAL	25.59842801	-0.393308994	1.524	1.33	H	0
5883	N	ASN	70.75741336	2.205580964	1.235	0.83	H	0
5884	R	ARG	84.03001072	2.969416106	1.692	1.441	H	0
5885	F	PHE	46.10575205	0.786883123	1.483	1.008	H	0
5886	N	ASN	85.22686674	3.038294914	1.108	0.659	H	0
5887	V	VAL	86.44158628	3.108201765	1.376	0.948	H	0
5888	A	ALA	81.93997856	2.849135202	1.426	0.917	H	0
5889	I	ILE	54.28724544	1.25772632	1.173	1.072	H	0
5890	T	THR	56.43086817	1.381091349	1.255	0.829	H	0
5891	R	ARG	86.26295105	3.097921346	1.201	1.552	E	0
5892	A	ALA	79.45694891	2.706237376	1.243	1.02	E	0
5893	K	LYS	54.71596999	1.282399326	1.488	1.354	E	1
5894	V	VAL	5.644873169	-1.541631812	1.548	1.366	C	2
5895	G	GLY	47.33833512	0.857818015	1.54	1.082	C	2
5896	I	ILE	44.99821365	0.723144525	1.334	1.105	E	2
5897	L	LEU	44.08717399	0.670714387	1.499	1.242	E	1
5898	C	CYS	35.44122901	0.173142101	1.354	1.173	E	1
5899	I	ILE	24.11575563	-0.478636473	1.782	1.576	E	5
5900	M	MET	42.94390854	0.604919704	1.797	1.406	E	6
5901	S	SER	30.65380493	-0.102373132	2.198	1.779	C	5
5902	D	ASP	20.81100393	-0.668824227	2.082	1.639	C	5
5903	R	ARG	28.65309039	-0.217513827	2.077	2.503	C	4
5904	D	ASP	4.019292605	-1.635183626	2.073	1.929	H	3
5905	L	LEU	42.42586638	0.575106489	2.45	1.695	H	3
5906	Y	TYR	16.93461951	-0.891909322	2.087	1.395	H	3
5907	D	ASP	20.65023223	-0.678076604	1.929	1.648	H	2
5908	K	LYS	4.32297249	-1.617706913	1.916	1.589	H	2
5909	L	LEU	46.46302251	0.807443962	1.743	1.531	H	2
5910	Q	GLN	11.20042872	-1.221910776	1.678	1.451	C	2
5911	F	PHE	44.73026081	0.707723896	1.381	1.023	C	2
5912	T	THR	23.1511254	-0.534150736	1.542	1.731	C	1
5913	S	SER	5.78778135	-1.533407476	2.477	1.872	T	1
5914	L	LEU	38.88888889	0.37155419	2.548	2.557	T	1
5915	E	GLU	3.929974991	-1.640323835	2.838	2.423	T	1
5916	I	ILE	2.715255448	-1.710230685	4.361	2.303	T	1
5917	P	PRO	3.840657378	-1.645464045	7.717	2.439	T	0
5918	R	ARG	3.912111468	-1.641351877	6.706	3.592	T	0
5919	R	ARG	3.679885673	-1.654716422	4.608	3.551	T	1
5920	N	ASN	4.32297249	-1.617706913	4.955	2.724	T	1
5921	V	VAL	4.126473741	-1.629015374	2.724	1.897	C	1
5922	A	ALA	3.751339764	-1.650604254	2.857	2.065	C	1
5923	T	THR	4.305108967	-1.618734955	2.332	1.998	C	0
5924	L	LEU	5.05537692	-1.575557195	3.466	3.451	C	0
5925	Q	GLN	4.305108967	-1.618734955	6.229	5.956	C	0

2.            I-TASSER server for protein structure and function prediction [Internet]. [cited 2020 Apr 12];Available from: https://zhanglab.ccmb.med.umich.edu/I-TASSER/

23.         Shu T, Huang M, Wu D, et al. SARS-coronavirus-2 nsp13 possesses NTPase and RNA helicase activities.

24.         Mirza MU, Froeyen M. Structural Elucidation of SARS-CoV-2 Vital Proteins: Computational Methods Reveal Potential Drug Candidates Against Main Protease, Nsp12 RNA-dependent RNA Polymerase and Nsp13 Helicase. 2020 [cited 2020 Apr 9];Available from: https://www.preprints.org/manuscript/202003.0085/v1